H. pylori infection is thought to be a causal factor in various skin disorders.
Henriette Farkas and colleagues from Semmelweis University, Budapest, Hungary, assessed the frequency of H. pylori infection in 65 patients with HAE.
HAE is characterized by non-itchy swellings, caused by non-histamine-like mediators. The disorder can be serious if swelling occurs in the face, throat, larynx, or gastrointestinal lining.
The investigators identified 19 of 65 HAE patients with H. pylori infection.
|19 of 65 HAE patients were infected with H. pylori.
| Lancet |
The frequency of abdominal symptoms was substantially higher in the infected group.
All patients with infection, and 11 of 46 without infection, had a history of recurrent episodes of acute abdominal pain (a common symptom of HAE).
H. pylori infection was successfully eradicated in 18 patients.
In 9 of 19 patients with dyspepsia, the frequency of episodes decreased from 100 over 10 months before H. pylori eradication, to 19 during the 10-month follow-up period.
The investigators conclude that screening for and eradication of H. pylori infection seems to be justified in patients with HAE.