Researchers from Edinburgh, Scotland, assessed the ability of the Rockall score to predict outcome in patients who undergo endoscopic therapy for peptic ulcer hemorrhage.
A total of 211 patients, admitted to the 3 major acute hospitals in Lothian, Scotland, were included in the retrospective study.
The patients were involved in 2 randomized trials of endoscopic therapy, between 1995 and 1999. Each patient was assessed and Rockall scores calculated.
All patients had ulcers, with active bleeding or non-bleeding visible vessels, requiring endoscopic therapy.
The patients were followed-up for 6 months.
The researchers compared mean Rockall scores in patients who did not rebleed, those who did rebleed, and those who died.
They also identified patients at greatest risk of rebleeding or death after endoscopic therapy.
|The higher the Rockall score, the greater the chance of rebleed and death.|
| European Journal of Gastroenterology & Hepatology |
Some 176 patients did not rebleed, with a mean Rockall score of 6.17.
Rebleeding occurred in 35 patients, whose mean score was 6.97.
There were 29 deaths, with mean score 7.34.
The differences between the 3 groups were found to be significant.
A total of 56 patients had a Rockall score of 8 or over. Of these, 16 (29%) re-bled and 14 (25%) died.
Of the 155 patients with scores of 7 or less, 19 (12%) re-bled and 15 (10%) died.
The difference between these groups was also found to be significant.
Author Nick I. Church, of the Western General Hospital, Edinburgh, concluded on behalf of his colleagues, "The Rockall score can be used to predict poor outcome in patients who undergo therapeutic endoscopy for major peptic ulcer bleeding."