A team from Cologne, Germany, investigated the demographic variations in the rising incidence of esophageal adenocarcinoma in white males.
Data on the incidence of adenocarcinoma of the esophagus, for each year since 1960, from 43 tumor registries in North America, Europe, and Australia was requested. Data from 22 centers was used.
The incidence of esophageal adenocarcinoma in white males was found to be rising in most countries.
Incidence rates in the year 2000 were estimated. The highest values were found in Great Britain (5.0-8.7 cases per 100,000 population) and in Australia (4.8 cases per 100,000 population). This was followed by the Netherlands (4.4 cases per 100,000 population), the United States (3.7 cases per 100,000 population), and Denmark (2.8 cases per 100,000 population).
Low rates (less than 1.0 cases per 100,000 population) were found in Eastern Europe.
Esophageal adenocarcinoma incidence highest in Great Britain.|
The researchers found the largest changes in incidence were in the Southern European countries. Here, the estimated average increase over six registries was 30% per year. In Australia, the average increase was 24% per year; and in the United States, it was 21% per year.
The rates of increase ranged from 9% to 18% on average in Northern Europe, Central Europe, and the United Kingdom.
In Eastern Europe, at most, there was a minor rise in incidence.
Dr Elfriede Bollschweiler, of the University of Cologne, concluded on behalf of the group, "In the Western industrialized nations, the analyzed data show that the incidence of adenocarcinoma of the esophagus has been rising rapidly in the last 20 years. The only exceptions to date are the countries of Eastern Europe."