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 17 November 2017

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News

Only 2% of children with indigestion have a peptic ulcer

Of 2,550 children presenting with upper gastrointestinal symptoms only 52 had peptic ulcers, according to an endoscopic study by doctors at the University of Athens, Greece.

News image

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Dr Eleftheria Roma and coworkers investigated the diagnosis and treatment of peptic ulcer disease in children over a period that covers the recent changes in management of the disease.

2,550 children with upper GI symptoms underwent upper gastrointestinal endoscopy over a 9-year period. Only 52 (2%) were diagnosed with primary peptic ulcers. Of these, 10 were gastric ulcers and 52 duodenal.

The median age of children with duodenal ulcers was 10.5 years, compared to a median age of 6.5 years for gastric ulcers.

There was no significant difference between the symptoms of patients with or without ulcers
European Journal of Pediatrics

Helicobacter pylori infection was significantly higher in patients with duodenal ulcers (62%) than in patients with gastric ulcers (20%).

1 month after H. pylori eradication treatment, 19 children underwent repeat endoscopy. This showed ulcer healing in 95% of patients in failure to eradicate H. pylori in 27% of patients.

During long-term follow up 6 children became symptomatic, of which 2 had duodenal ulcer associated with H. pylori infection.

Dr Roma concludes, "Successful H. pylori eradication results in long-term healing of ulcers in children."

Eur J Pediatr 2001; 8: 497-500
27 July 2001

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