Difficulties and shortages associated with cadaveric liver donation have meant that living-related donor liver graft transplantation has become a popular alternative to whole-organ transplantation.
Dr Yasuhiko Hashikura and colleagues at Shinshu University, Japan, reviewed the records of 110 patients who underwent LRLT over a 10-year period.
The recipients of the grafts included 78 adults and 38 children. Grafts varied between 26% and 192% of the recipient's standard liver volume.
1 year: 88%
3 years: 85%
5 years: 85%
The researchers calculated 1-, 3-, and 5-year patient survival rates of 88%, 85%, and 85%, respectively.
Patient survival rate could be predicted by ABO compatibility of donor and recipient. Patient age, underlying disease, donor-recipient relation, donor age, and graft volume did not affect survival rate.
All donors are reported as having excellent long-term liver function, with no complications after graft donation.
Dr Hashikura concludes, "Cautious expansion of this procedure may be justified under the situation of serious shortage of cadaveric donors."