A team from Durham, North Carolina, USA, investigated the incidence of Dieulafoy lesions among patients who underwent endoscopic examination between 1993 and 1999.
During this 6-year period, 40 Dieulafoy lesions were identified on upper endoscopy, at the researchers' institution. Of these, 7 were located in the duodenum and one in the right colon.
47% of patients were hospitalized for other causes before onset of bleeding.
|90% of patients with Dieulafoy lesions were successfully treated endoscopically.
|Am J Gastroenterol|
17 of 40 (43%) were found to have other abnormal findings at endoscopy.
The researchers found that in 90% of the cases, endoscopic treatment for Dieulafoy lesions was successful.
Seven patients died, but none as a result of hemorrhage.
In 24 endoscopically-treated patients, in whom follow-up data was available, Dieulafoy bleeding recurred in a single patient.
Dr Nathan Schmulewitz, of the Duke University Medical Center, Durham, concluded on behalf of the group, "Dieulafoy lesions are rare and often difficult to diagnose. However, they must be considered in the evaluation of upper and lower GI tract hemorrhage, as they can usually be managed endoscopically."