Researchers from Boston, Massachusetts, USA determined whether preoperative factors could accurately predict postoperative relief of gastro-esophageal reflux disease symptoms, following laparoscopic antireflux surgery.
100 consecutive patients undergoing laparoscopic antireflux surgery were enrolled in the study. Each completed a detailed preoperative questionnaire, and underwent endoscopy, manometry, and 24-hour esophageal pH monitoring.
Two surgeons performed all procedures in a standardized fashion.
At least 2 months following operative intervention, a single interviewer recorded Visick and Gastro-esophageal Reflux Disease-Health-Related Quality of Life scores for all patients. The interviewer was blinded to all preoperative information and procedure performed.
All follow-ups were performed within 3 years of antireflux procedure.
The surgical success rate, as defined by Visick scores of 1-2, was found to be 91%.
|91% of surgical procedures to control GERD symptoms were successful.|
|Am J Surg|
The researchers found that three variables were predictive of postoperative success. These were an age less than 50 years, the presence of typical symptoms at presentation, and complete resolution of symptoms with acid suppression therapy.
Patrick G. Jackson, of the Department of Surgery, Massachusetts General Hospital, said on behalf of the team, "The study shows that surgical strategies can reproducibly control gastro-esophageal reflux disease symptoms in more than 90% of patients."
"The optimal surgical candidate is a patient under the age of 50 whose typical symptoms completely resolve with acid suppression therapy," he concluded.