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 22 November 2017

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News

Quality of life questionnaires differ in ulcerative colitis

Quality of life questionnaires after restorative proctocolectomy for ulcerative colitis lead to different interpretations, finds the latest Archives of Surgery.

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Some studies show that health-related quality-of-life scores for patients who undergo restorative proctocolectomy for ulcerative colitis are similar to healthy controls.

Other studies show evidence that these patients experience a health-related quality of life similar to those with mild ulcerative colitis or in remission.

The discrepancy in health-related quality-of-life scores among studies may be due to different health-related quality-of-life analyses.

Dr Marco Scarpa and colleagues from Italy consecutively enrolled 24 patients with ulcerative colitis, 24 patients with Crohn disease, and 24 healthy controls.

In the second phase of the study, the team enrolled 40 patients who underwent restorative proctocolectomy.

The Italian Cleveland Global Quality of Life instrument had good construct validity
Archives of Surgery

The research team assessed a further 43 patients with ulcerative colitis, and 44 controls in the second phase of the study.

The team administered an Italian version of the Cleveland Global Quality of Life instrument.

The Padova Inflammatory Bowel Disease Quality of Life instrument, and the Italian 36-Item Short-Form Health Survey were also used.

The team evaluated the construct validity, internal consistency, test-retest reliability, and sensitivity to change.

In addition, the researchers evaluated the discriminant ability of the Italian Cleveland Global Quality of Life instrument.

The team compared its discriminative ability with that of the Padova Inflammatory Bowel Disease Quality of Life instrument.

The researchers found that the Italian Cleveland Global Quality of Life instrument obtained good construct validity.

The team noted that this instrument showed good internal consistency, test-retest reliability, and sensitivity to change.

The Italian Cleveland Global Quality of Life score did not distinguish patients who underwent restorative proctocolectomy from healthy controls.

The questionnaire also did not distinguish those with mild ulcerative colitis or ulcerative colitis in remission.

The Padova Inflammatory Bowel Disease Quality of Life instrument reported similar scores for all patients but showed a difference vs healthy controls.

Dr Scarpa's team concluded, “We validated an Italian version of the Cleveland Global Quality of Life score.

“The different results obtained with the Cleveland Global Quality of Life and the Padova Inflammatory Bowel Disease Quality of Life instruments can be attributed to the different discriminative ability of the 2 questionnaires.”

Arch Surg 2007: 142(2): 158-65
09 March 2007

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