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News

Quality of life a clinical indicator for chronic pancreatitis

The information given by quality-of-life assessments should be included in the work-up of patients affected by chronic pancreatitis, finds this month's Pancreas.

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There are no data available that evaluate the possible modifications of the quality of life during the clinical course of chronic pancreatitis.

Dr Raffaele Pezzilli and colleagues evaluated the outcome for patients with chronic pancreatitis in a 2-year follow-up study.

The team used the Short Form 12 Health Survey Italian version questionnaire.

The questionnaire generated 2 summary scores including the physical component summary-12 and the mental component summary-12.

The physical component summary-12 score worsened in 21%
Pancreas

The researchers studied 83 patients with chronic pancreatitis with a mean interval time of 2 years between the first and the second evaluation.

The research team found that there was a significant increase in the frequency of diabetes mellitus, nonpancreatic surgery, and comorbidities.

The physical component summary-12 and mental component summary-12 were not significantly different in comparison with the baseline evaluation.

The physical component summary-12 score worsened in 21% of patients, and 53% of patients had a stable physical component summary-12 score.

The researchers observed that 27% improved their physical component summary-12 score.

Regarding the mental score, 18% of patients worsened, 63% had a stable mental component summary-12 score.

The team noted that 19% of patients improved their mental component summary-12 score.

Only age at diagnosis was significantly related to the change of the mental component summary-12 score.

Dr Pezzilli's team comments, “The information given by quality-of-life assessment should be routinely included in the work-up of patients affected by chronic pancreatitis.”

“The information should select those patients with severely impaired physical and mental scores, and to plan an intensive program of medical and psychological follow-up.”

Pancreas 2007: 34(2): 191-6
07 March 2007

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