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 25 November 2017

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News

PPIs are the main long-term treatment choice for GERD

The latest issue of Alimentary Pharmacology & Therapeutics finds that continuous PPI intake is the predominant treatment pattern in patients with GERD.

News image

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Gastro-esophageal reflux disease (GERD) is a common condition frequently requiring long-term pharmacological treatment.

Dr Nocon and colleagues from Germany described the long-term pattern of GERD medication use patients receiving routine care.

GERD medication use was constant over 4 years
Alimentary Pharmacology and Therapeutics

The team recruited patients as part of the ongoing pro GERD study, a 10-year-cohort study including 6215 patients at baseline.

The researchers assessed GERD medication and symptoms with patient questionnaires.

During follow-up, medical treatment was prescribed by participating primary care physicians.

The team analyzed associations between patient characteristics and medication by logistic regression.

The researchers found that the percentage of patients who reported using any GERD medication remained constant from year 1 to year 4.

Of patients who reported using GERD medication, the team observed that the majority were taking proton pump inhibitors (PPIs).

Continuous proton pump inhibitors intake was the predominant prescription pattern.

The research team noted that this was followed by on-demand treatment.

Dr Nocon's team concluded, "The majority of the GERD population in our study reported long-term treatment using proton pump inhibitors."

"Continuous proton pump inhibitor intake therefore was the predominant treatment pattern."

"The proportion of patients taking a proton pump inhibitors on a continuous basis remained constant over time."

Aliment Pharmacol Ther 2007: 25(6): 715-22
27 February 2007

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