Pancreatic cancer is an aggressive cancer with low survival time, with health-related quality of life being of major importance.
Dr Jacqueline Müller-Nordhorn and colleagues from Germany assessed both generic and disease-specific health-related quality of life in patients with pancreatic cancer.
The team included 45 patients with pancreatic cancer at admission to hospital.
The patients' mean age was 64 years, and 53% were females.
|44% of patients had metastases at the time of admission|
The researchers determined health-related quality of life with the disease-specific European Organization for Research and Treatment of Cancer instrument.
The team also used the generic EuroQoL-5D health status instrument.
The researchers then compared scores of patients to those of norm populations.
The association of symptoms with overall health-related quality of life was analyzed using linear regression.
A total of 45 patients with pancreatic cancer were included.
The team found that 44% of patients had metastases at the time of admission.
Health-related quality of life was impaired for most European Organization for Research and Treatment of Cancer and EuroQoL-5D scales.
The researchers noted that symptoms of fatigue, and pain were significantly associated with impaired overall health-related quality of life.
Dr Müller-Nordhorn's team concludes, “Health-related quality of life was severely impaired in patients with pancreatic cancer.”
“Symptom control and palliative care appear to be of particular importance.”