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 17 January 2018

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News

Pancreatic cancer impairs health-related quality of life

Health-related quality of life is severely impaired in patients with pancreatic cancer, finds the most recent issue of Digestion.

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Pancreatic cancer is an aggressive cancer with low survival time, with health-related quality of life being of major importance.

Dr Jacqueline Müller-Nordhorn and colleagues from Germany assessed both generic and disease-specific health-related quality of life in patients with pancreatic cancer.

The team included 45 patients with pancreatic cancer at admission to hospital.

The patients' mean age was 64 years, and 53% were females.

44% of patients had metastases at the time of admission
Digestion

The researchers determined health-related quality of life with the disease-specific European Organization for Research and Treatment of Cancer instrument.

The team also used the generic EuroQoL-5D health status instrument.

The researchers then compared scores of patients to those of norm populations.

The association of symptoms with overall health-related quality of life was analyzed using linear regression.

A total of 45 patients with pancreatic cancer were included.

The team found that 44% of patients had metastases at the time of admission.

Health-related quality of life was impaired for most European Organization for Research and Treatment of Cancer and EuroQoL-5D scales.

The researchers noted that symptoms of fatigue, and pain were significantly associated with impaired overall health-related quality of life.

Dr Müller-Nordhorn's team concludes, “Health-related quality of life was severely impaired in patients with pancreatic cancer.”

“Symptom control and palliative care appear to be of particular importance.”

Digestion 2006: 74(2): 118-25
09 February 2007

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