Helicobacter pylori eradication from the oral cavity is more difficult than from the stomach.
Thus, if the bacterium survives the antibacterial therapy in the oral cavity, it would be able to re-infect the stomach within a few weeks.
Oral health status could correspond to oral infection with H pylori.
Dr Zbigniew Namiot and colleagues from Poland determined whether oral health and oral hygiene practices affect the efficacy of H pylori eradication from the stomach.
The researchers evaluated 137 patients with peptic ulcer who had undergone a 7-day course of eradication treatment.
|Brushing teeth twice a day reduced the efficacy of H pylori eradication|
Treatment in Group 1 included omeprazole, amoxicillin, and tinidazole vs omeprazole, clarithromycin, and tinidazole in Group 2.
The efficacy of H pylori eradication from the stomach was evaluated at the second gastroscopy 4 weeks after cessation of eradication therapy.
The research team measured the effects of the eradication therapy by rapid urease test and histology.
The team examined natural dentition and prosthetic restorations.
In addition, the researchers assessed hygienic procedures referring to natural dentition, and dentures accompanied the second gastroscopy.
There was no association between the efficacy of H pylori eradication, and the number of natural teeth, decayed teeth, or use of dentures.
The researchers observed no association between the efficacy of H pylori eradication and debris index, or periodontal index.
However, the team noted an association between eradication success, and some oral hygiene procedures.
In Group 1, dental prosthesis removal for the night and brushing the natural teeth twice a day or more reduced the efficacy of H pylori eradication.
Dr Namiot's team concludes, “Oral health and oral hygiene practices seem unlikely to increase the efficacy of H pylori eradication from the stomach.”