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 25 February 2018

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News

US fatality rates for acute pancreatitis have not reduced

This month's issue of Pancreas shows that incidence rates of acute pancreatitis have risen, with no reduction in case-fatality rates in the US.

News image

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Dr Charles Frey and colleagues defined the epidemiology of acute pancreatitis in a racially diverse population.

Analysis of all patients hospitalized in California with first-time acute pancreatitis for the period between 1994 and 2001.

Subtypes were classified based on the presence or absence of predisposing conditions.

There were 70,231 patients hospitalized for first-time acute pancreatitis.

Acute pancreatitis rose between 1994 and 2001
Pancreas

The research team found that 33% had biliary tract disease alone, 20% had alcohol abuse alone, and 37% were idiopathic.

The age-standardized incidence increased by 32% from 33 to 44 cases per 100,000 adults for the period between 1994 and 2001.

The team noted that the largest increase occurred in the biliary group.

The standardized incidence rate of alcoholic and idiopathic pancreatitis was highest in African Americans.

The researchers observed that biliary pancreatitis was highest in Hispanics.

The team found no change over time in the percentage of patients dying in the first 14 or 91 days.

Using a risk-adjusted model, the team showed that patients with alcoholic pancreatitis had the highest risk of dying.

Dr Frey's team concludes, “The incidence rate of acute pancreatitis rose for the period between 1994 and 2001.”

“However, there was no reduction in the 14- or 91-day case-fatality rate.”

“Further research is needed to explain both the rise in the incidence rate of pancreatitis, and the absence of any improvement in the early case-fatality rate.”

Pancreas 2006: 33(4): 336-44
14 November 2006

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