Emerging evidence indicates that hyperglycemia and hyperinsulinemia may be implicated in the development of pancreatic cancer.
Frequent consumption of sugar and high-sugar foods may increase the risk of pancreatic cancer by inducing frequent postprandial hyperglycemia.
It also increases insulin demand, and decreases insulin sensitivity.
Dr Susanna Larsson and colleagues from Sweden prospectively examined the association of added and high-sugar foods with the risk of pancreatic cancer.
The researchers evaluated a population-based cohort study.
|Hazard ratios for soft drinks was 1.9|
|American Journal of Clinical Nutrition|
A food-frequency questionnaire was completed in 1997 by 77,797 women and men aged 45 to 83 years.
The research team had no previous diagnosis of cancer or history of diabetes.
The participants were followed through 2005.
During a mean follow-up of 7 years, the team identified 131 incident cases of pancreatic cancer.
The consumption of added sugar, soft drinks, and sweetened fruit soups or stewed fruit was positively associated with the risk of pancreatic cancer.
The researchers compared hazard ratios for the highest with the lowest consumption categories were 1.7 for sugar.
The team noted that the hazard ratios for the highest with the lowest categories for soft drinks was 1.9, and 1.5 for sweetened fruit soups or stewed fruit.
Dr Larsson's concludes, “High consumption of sugar and high-sugar foods may be associated with a greater risk of pancreatic cancer.”