Despite the global increase in the incidence of intrahepatic cholangiocarcinoma, regional variations occur.
Drs Tushar Patel and Luciana McLean from Texas assessed the epidemiology of these cancers in different racial and ethnic groups in the United States.
Disease prevalence, mortality and survival rates for different racial and ethnic groups were obtained from the surveillance database.
The researchers also accessed the epidemiology and end results survey database.
The research team found that the age-adjusted prevalence was highest for Hispanics, and lowest for Blacks.
|Mortality rates increased by greater than 3% annually |
Age-adjusted mortality rates were higher for American Indian/Alaska Natives and Asian/Pacific Islanders compared with other groups.
The team noted that mortality rates increased by greater than 3% annually for all racial or ethnic groups.
However, the researchers found that for American Indian/Pacific Islanders the mortality rates decreased by under 1% annually.
The increase in mortality rates was greatest for Hispanic women aged between 40 and 49 years.
The team observed that prevalence and survival were significantly higher in Hispanic women in contrast to gender differences observed in other groups.
Dr Patel and colleague conclude, “Significant racial and ethnic variations occur in the epidemiology of intrahepatic cholangiocarcinoma within geographically defined regions in the United States.”
“These may reflect genetic, socioeconomic or cultural predispositions to cancer.”