Common risk factors exist in colorectal neoplasia and coronary artery disease.
Dr Chan and colleagues from Hong Kong investigated in a retrospective study if there is coexistence of the 2 events in patients 50 years and older.
The research team retrieved computer data on colonoscopies performed on symptomatic patients.
The team also assessed the corresponding medical record and colonic histology in these patients from 1997 to 2000.
History of coronary artery disease was recorded.
The researchers used logistic regression analysis to adjust for the factors of age and sex, bivariate, and to test for coexistence.
The team reported that 1382 patients were recruited.
| Male was the predominant sex only in colorectal cancer|
|Alimentary Pharmaoclogy & Therapeutics|
Colorectal neoplasia and history of coronary artery disease were present in 27% and 12% of patients, respectively.
The researchers observed that the mean age of patients was older in colorectal neoplasia, and in coronary artery disease patients.
Male was the predominant sex in colorectal neoplasia, but not in coronary artery disease.
The team noted that colorectal neoplasia patients were more likely to have coronary artery disease.
Bivariate logistic regression analysis showed strong association between the 2 events.
Dr Chan's team concludes, “There is strong coexistence of colorectal neoplasia and coronary artery disease, probably due to exposure to common risk factors.”