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 21 May 2018

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News

Peptic ulcer mortality rates have declined in Scotland

Mortality rates for peptic ulcer have declined in Scotland over the last decade, however admission rates increased for older patients, finds this month's Alimentary Pharmacology & Therapeutics.

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While overall hospital admission rates for peptic ulcer declined in England in the 1990s, they increased among the elderly, especially for complicated ulcer.

However, peptic ulcer admissions fell for all age groups in the United States.

Dr Kang and colleagues examined time trends in hospital admissions, mortality and operations because of peptic ulcer in Scotland from 1982 to 2002.

The researchers also assessed the use of various drugs relevant to the etiology and treatment of peptic ulcer from 1992 to 2002.

The researchers found that there was a general decrease in admission rates, especially for younger individuals.

For individuals aged above 74 years, admission rates increased for gastric ulcer with hemorrhage among men.

The research team noted that admission rates increased for duodenal ulcer hemorrhage between both sexes for individuals above 74 years.

The number of operations fell, especially for younger patients
Alimentary Pharmacology & Therapeutics

The number of operations fell dramatically, especially for younger patients.

Mortality rates generally declined.

The team observed that case fatality rates were greater for women than men.

Fatality rates declined over the study period for gastric ulcer, but increased for duodenal ulcer.

The use of low-dose aspirin, oral anticoagulants, selective serotonin reuptake inhibitors and proton-pump inhibitors increased.

However, the team noted that the use of non-steroidal anti-inflammatory drugs and histamine-2 antagonists declined.

Dr Kang's team concluded, “Admission rates for peptic ulcer generally fell for younger individuals, but increased for older people with hemorrhage.”

Aliment Pharmacol Ther 2006: 24(1): 65
23 June 2006

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