Restorative proctocolectomy with ileoanal anastomosis is the surgical standard for patients with ulcerative colitis.
Significant reduction in female fertility and fecundity after this technique has been shown in recent studies.
In selected cases, colectomy with ileorectal anastomosis is another surgical option.
Dr Pierre-Eugène Mortier and colleagues from France assessed fertility in women with ulcerative colitis who underwent ileorectal anastomosis.
The team's study included all women with ulcerative colitis.
The patients underwent ileorectal anastomosis between 1962 and 1999.
The patients were 40 years or younger at the time of surgery, and older than 18 years of age at the time of the interview.
The team of doctors collected data using a structured telephone interview concerning reproductive behavior and waiting times to pregnancy.
The doctors reported that among 40 eligible patients, 37 whose mean age at ileorectal anastomosis was 28 years answered the questionnaire.
|10 of 15 females after ileorectal anastomosis became pregnant|
|Gastroenterologie Clinique et Biologique|
The team noted that 22 were unmarried, not wishful of pregnancy and/or already had children.
Among 15 females wishing children after ileorectal anastomosis, 10 became pregnant.
The team identified that 1 patient had a therapeutic abortion, 2 had a miscarriage, 4 had 1 child, 2 had 2 children and 1 had 4 children.
In addition, the team observed that 5 patients were sterile after ileorectal anastomosis.
Dr Mortier's team commented, “These preliminary results suggest that ileorectal anastomosis for ulcerative colitis preserves female fertility.”
“If confirmed in other series, this information should be provided to young women with ulcerative colitis before deciding on surgical options.”