Little is known about compliance with colonoscopy as a screening method in first-degree relatives of patients with large adenomas.
Dr Bonithon-Kopp and colleagues from France evaluated the compliance and the determinants of screening colonoscopy among this population.
The research team obtained data from the family part of the GEADE study, a study on genetic factors of colorectal adenomas.
The team identified 306 patients with adenomas as index cases.
All living first-degree relatives aged 40 to 75 who could be contacted by the index case were asked to undergo a colonoscopy.
| Compliance was higher in relatives under than over 55 years of age|
|Alimentary Pharmacology & Therapeutics|
Those who had undergone colonoscopy in the previous 5 years were not included in the study.
The researchers found among 674 eligible relatives, 56 had had a colonoscopy within the preceding 5 years.
A further 114 relatives underwent a screening colonoscopy resulting in a compliance with screening colonoscopy of 18%.
This was not related to most characteristics of index cases.
The team found that compliance was significantly lower when the index cases lived in the Greater Paris area than when they lived in other areas.
Compliance was higher in siblings and offspring than in parents, and in relatives under 55 years old than in relatives aged 55 and over.
Dr Bonithon-Kopp's team commented, “Compliance with colonoscopy was low in first-degree relatives of patients with large adenomas.”
“The reasons for this should be determined and appropriate strategies developed to increase compliance.”