Pancreatic cancer is the 4th leading cause of cancer death in the United States.
Dr Shaib and colleagues from Texas examined temporal changes in the incidence and survival of patients with pancreatic adenocarcinoma.
The research team used data from 9 registries of the Surveillance Epidemiology and End Results programme.
The team calculated age-adjusted incidence rates per 100 000 and survival rates for pancreatic cancer between 1977 and 2001.
The researchers identified 58,655 cases of pancreatic cancer.
| Men were 30% more affected than women|
|Alimentary Pharmacology & Therapeutics|
The age-adjusted incidence rate remained stable during the study period.
Overall, the team noted that men were 30% more affected than women.
The age-adjusted incidence rates were almost 50% higher among Blacks than Whites and people of other races.
Over time the proportions of patients with localized disease decreased from 12% to 7%.
The researchers found that those with regional disease increased from 19% to 26%, while metastatic disease remained stable at around 50%.
The 1-year relative survival increased from 15 % between 1977 and 1981 to 22% between 1997 and 2001.
Dr Shaib's team commented, “The incidence of pancreatic cancer is stable.”
“A shift from localized to regional disease was observed over time.”
“The overall survival remains poor despite important improvements among patients with early stage disease.”