It has been suggested that the incidence of inflammatory bowel disease (IBD), Crohn's disease, ulcerative colitis, and indeterminate colitis has been continuously increasing.
Dr Ida Vind and colleagues from Denmark described contemporary IBD incidence rates and patient characteristics in Copenhagen County and City.
The research team prospectively followed all patients diagnosed with IBD during 2003 to 2005.
Demographic and clinical characteristics, such as disease extent, extraintestinal manifestations, smoking habits, medical treatment, surgical interventions, cancer, and death, were registered.
The team reported that 562 patients were diagnosed with IBD, resulting in mean annual incidences of 9 in 105 for Crohn's disease, 13 in 105 for ulcerative colitis, and 1 in 105 for indeterminate colitis.
Time from onset to diagnosis was 8 months in Crohn's disease and 5 months in ulcerative colitis patients.
|12% of Crohn's patients vs 6% with ulcerative colitis had surgery during the year of diagnosis |
|American Journal of Gastroenterology|
The researchers found that a family history of IBD, smoking, and extraintestinal manifestations was significantly more common in Crohn's disease than in ulcerative colitis patients.
Only about 1% of ulcerative colitis patients had primary sclerosing cholangitis.
In Crohn's disease, the team noted that old age at diagnosis was related to pure colonic disease, whereas children significantly more often had proximal and extensive involvement.
The researchers observed that 12% of Crohn's patients, and 6% of ulcerative colitis patients underwent surgery during the year of diagnosis.
These results are significantly less than earlier reported.
Dr Vind's team commented, “The incidence of IBD in Copenhagen increased noticeably during the last decades.”
“Time from onset of symptoms until diagnosis decreased markedly, extent of Crohn's was related to age at diagnosis, and the risk of surgery was low in ulcerative colitis.”