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 22 November 2017

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News

Low GI rebleeding rates after negative capsule endoscopy

Negative capsule endoscopy in obscure gastrointestinal bleeding has a very low rebleeding rate, and further invasive investigations can be deferred, finds the latest American Journal of Gastroenterology.

News image

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Capsule endoscopy is one of the widely accepted investigations for obscure gastrointestinal bleeding.

Little is known about the impact of capsule endoscopy on the long-term outcome of these patients.

Dr Leung and colleagues studied the long-term outcome of endoscopy in obscure gastrointestinal bleeding.

The team of doctors evaluated 49 patients with obscure gastrointestinal bleeding, of which 45% were men with a mean age of 58 years.

The cumulative rebleeding rate was 6% with a negative capsule endoscopy
American Journal of Gastroenterology

The most clinically relevant finding that was related to bleeding was identified by capsule endoscopy.

The team followed up all patients for at least 12 months for clinical overt and occult bleeding.

Possible bleeding lesions were detected by capsule endoscopy in 63% of patients.

The doctors reported that 31% patients underwent further interventions including laparotomy, and push enteroscopy.

The overall long-term rebleeding rate in this cohort was 33%.

The cumulative rebleeding rate was lower at 6% with a negative capsule endoscopy vs 48% in patients with a positive capsule endoscopy.

The sensitivity and negative predictive values of capsule endoscopy in predicting rebleeding were both 94%.

Dr Leung's team commented, “Patients with obscure gastrointestinal bleeding and negative capsule endoscopy had a very low rebleeding rate, and further invasive investigations can be deferred.”

Am J Gastroenterol 2006: 101(6): 1224
08 June 2006

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