Sexual dysfunction has been reported in patients with hepatitis C virus (HCV) infection.
In this study, doctors from the United States evaluated the prevalence of sexual dysfunction in men with chronic HCV infection. They also assessed the impact of this dysfunction on health-related quality of life.
|HCV positive men had greater sexual dysfunction.|
|American Journal of Gastroenterology|
The team included 112 HCV positive men and 239 HCV negative controls.
Patients completed the Brief Male Sexual Function Inventory (BMSFI), Beck Depression Inventory, and the Medical Outcomes Study Short Form-36. These questionnaires evaluated sexual function, depression, and quality of life, respectively.
The doctors found that HCV positive men had significantly more sexual dysfunction than control subjects across all 5 domains of the BMFSI.
In addition, HCV-infected men were significantly more likely than the controls to not be sexually satisfied (54%vs 29%).
Furthermore, in the subjects without depression, HCV positive men were more likely to not be sexually satisfied when compared with the controls (48%vs 11%).
The team determined that HCV-infected men who were not sexually satisfied scored poorly in 6 of the 8 domains of quality of life assessment, compared with HCV-infected men who were sexually satisfied.
Dr Ann Danoff's team concluded, "Sexual dysfunction is highly prevalent in men with chronic HCV infection, is independent of depression, and is associated with a marked reduction in health-related quality of life ".