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 20 April 2018

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News

Increasing inflammatory bowel disease in northern Denmark

There has been a marked increase in both ulcerative colitis and Crohn's disease during the last 25 years in Denmark, find researchers in the June issue of the European Journal of Gastroenterology and Hepatology.

News image

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The incidence rates of inflammatory bowel disease have been well documented. However, there are few long-term population-based studies examining trends through time.

In this study, researchers examined the incidence rate of IBD over a 25-year study period and estimated the prevalence in 2002.

The team included 2326 incident cases diagnosed between 1978 and 2002. They used all patients (n=2205) living in North Jutland County on 31 December 2002 to estimate prevalent cases.

The researchers calculated age-specific and gender-specific standardized incidence rates.

Ulcerative colitis and Crohn's has increased in both genders.
European Journal of Gastroenterology & Hepatology

The team found that, in women, incidence rates for ulcerative colitis increased from 8 per 100,000 person-years in 1978-1982 to 17 in 1998-2002. In men, the increase in incidence rates was similar.

Crohn's disease incidence rates in women increased from 4 per 100,000 person-years in 1978-1982 to 11 in 1998-2002. In men, incidence rates increased from 3 to 9 per 100,000 person-years.

The research team determined that the prevalence of ulcerative colitis and Crohn's disease was 294 and 151 per 100,000 inhabitants, respectively.

Dr Jacobsen's team concluded, "A marked and parallel increase was seen in both ulcerative colitis and Crohn's disease in both genders during the last 25 years, with a corresponding high prevalence of both diseases".

Eur J Gastroenterol Hepatol 2006; 18(6): 601-6
23 May 2006

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