Over 3.5 years, 55 right and 55 left in vivo split grafts were transplanted in Los Angeles and Irvine, USA. The 102 pediatric and adult recipients were followed for a median of 14.5 months.
The variables of the recipients, donors and transplant surgery were examined to determine their effect on patient survival.
Importantly, survival rates of split graft recipients were similar to those after whole organ transplantation; right and left graft survival rates were also similar (80 and 76% at 14.5 months).
High-risk recipients had a survival rate significantly lower than non-urgent recipients.
High-risk recipient status and number of transplants per patient were factors associated with a significantly increased mortality risk.
Overall, the variables influencing the outcome of split liver transplantation are similar to those in whole organ transplantation - encouraging further utilization of this technique.