Rates and time trends in mortality from pancreatic cancer vary considerably between countries.
Dr Wood and colleagues from England examined trends and patterns in the incidence of pancreatic cancer in England and Wales.
The investigative team also assessed the survival and mortality from pancreatic cancer in those countries from 1975 to 2000.
The team evaluated whether incidence and survival rates are related to socio-economic deprivation.
The annual age-specific and overall age-standardized incidence and mortality rates by sex for pancreatic cancer in total, and by subsite were calculated.
The team also estimated survival by sex and age group and by subsite.
The investigators found that results in males, and the age-standardized rate fluctuated in the late 1970s, to peak at 13 per 100 000.
|Survival rates were only 2% to 3% at 5 years from diagnosis|
|Alimentary Pharmacology & Therapeutics|
In 1979, it declined steadily by an average of 1% per year to around 10 per 100 000 in the mid-1990s and then levelled off.
For females, the team noted that the rate peaked at 8 per 100 000 in the late 1980s before declining and fluctuating around 8 per 100 000 in the late 1990s.
Patterns and trends in mortality rates were closely similar to those in incidence, due to the very low survival rates.
The investigators observed that survival rates were only 2% to 3% at 5 years from diagnosis.
Survival rates improved only minimally over the period from 1971 to 1999.
Incidence and mortality rates were slightly higher in both males and females living in the most deprived areas.
The team found that survival was not consistently related to socio-economic deprivation.
Dr Wood's team concluded, “The incidence of, and mortality from, pancreatic cancer in England and Wales have fallen from peak levels observed in the 1970s and 1980s, and levelled off in the 1990s for both sexes.”
“However, survival rates remain very low.”