Inflammatory bowel disease (IBD) has been uncommon in China until about 1990, but since then, it has been seen in the clinical setting more and more.
The prevalence and phenotype of inflammatory bowel disease in the Chinese population is not well known.
Dr Li Jiang and colleagues investigated the trend of prevalence in ulcerative colitis and Crohn's disease in central China.
The research team evaluated clinical features, extraintestinal manifestations, and the treatment of inflammatory bowel disease in the last 14 years.
The team collected retrospectively 389 patients with ulcerative colitis and 63 patients with Crohn's disease from 5 central hospitals in Wuhan City.
|Male to female ratio with IBD was 1.5:1 in ulcerative colitis, and 2.3:1 in Crohn's|
|Inflammatory Bowel Diseases|
High-quality endoscopic and histological diagnoses were available from 1990 to 2003.
Ulcerative colitis and Crohn's disease were diagnosed from clinical, radiological, endoscopic, and histological examinations according to Lennard-Jones criteria.
The researchers found that the prevalence of ulcerative colitis and Crohn's disease increased between 1990 and 2003.
The team noted no change in the sex and age distribution from 1990 to 1996 compared with 1997 to 2003, both in ulcerative colitis and Crohn's.
However, patients with ulcerative colitis and with higher education and a professional occupation increased during 1997 to 2003 compared with 1990 to 1996.
The mean age of patients with Crohn's disease was significantly younger than that of ulcerative colitis at the time of diagnosis.
The team observed that the ratio of male to female patients was 1.5:1 in ulcerative colitis, and 2.3:1 in Crohn's disease, respectively.
The mean duration of onset of the disease to diagnosis was 1 year in ulcerative colitis, and Crohn's disease.
The extra intestinal manifestations of ulcerative colitis and Crohn's disease were 6% and 19%, respectively.
The researchers found that complications of ulcerative colitis and Crohn's disease were 6% and 51%, respectively.
Only 3% of ulcerative colitis patients required surgery, whereas 27% of Crohn's disease patients underwent surgical procedures.
Dr Jiang and colleagues concluded, “The prevalence of inflammatory bowel disease has increased in Wuhan City, central China, but is not as high as in Western countries.”
“The disease in Wuhan City has often been associated with young adult professional males with a high level of education.”
“The clinical presentation of ulcerative colitis was often mild and had few extra intestinal manifestations.”