Researchers from the North Tyneside Hospital, North Shields, England, investigated the prevalence of functional gastrointestinal disorders (FGIDs) in people with infectious diarrhea (ID) compared with controls.
Cases with positive bacterial stool cultures were invited to complete the Rome II modular questionnaire. This assessed bowel symptoms over the preceding year before their recent
gastroenteritis. The FGID's looked at were functional dyspepsia, IBS, and functional diarrhea.
Age- and sex-matched controls were approached from the same general practices as the cases, and completed the same questionnaire.
|Subjects with infectious diarrhea were five times more likely to have pre-existing IBS.
|British Society of Gastroenterology Annual Meeting|
The Odds Ratio for a case having a pre-existing FGID, compared with a control, was found to be 4.74. Looking at IBS only, the Odds Ratio for a case having pre-existing IBS compared to a control was 5.04.
Patients presenting to their GP with ID had a pre-existing high rate of FGID's, particularly IBS, compared to a matched community-based control group, commented the authors.
Researcher S. D. Parry concluded on behalf of the group, "Studies that examine rates of new FGID's after ID need to carefully exclude patients with pre-existing FGID's.
"As only a small percentage of patients with ID present to their GP, consultation behavior is likely to produce the results that other authors have obtained in the past."