Crohn's disease has a negative impact on patients' perception of health.
Several factors, such as disease activity, influence health-related quality of life impairment.
However, the effect of the phenotypic Crohn's disease characteristics recognized in the Vienna classification on health-related quality of life remains unknown.
Dr Francesc Casellas and colleagues from Spain measured health-related quality of life in Crohn's disease patients using 3 questionnaires.
|Female sex is an independent variable for worse health-related quality of life scores|
|American Journal of Gastroenterology|
The team used the Spanish version of the Inflammatory Bowel Disease Questionnaire, the Psychological General Well-Being Index, and the EuroQol.
The researchers included 198 Crohn's disease patients.
The team found that scores for the 3 questionnaire dimensions did not differ according to age at diagnosis, disease location or disease behavior.
Multivariate analysis identified independent variables for worse health-related quality of life including female sex, and higher number of relapses per year.
The researchers also observed that worse clinical disease activity was an independent variable for worse health-related quality of life.
None of the 3 Vienna variables reached statistical significance.
Dr Casellas' team concluded, “Health-related quality of life impairment in Crohn's disease patients is independent of the clinical variables established in the Vienna classification for phenotypic type of disease.”