Help
Subscribe


GastroHep.com - the global online resource for all aspects of gastroenterology, hepatology and endoscopy

 17 January 2018

Advanced search
GastroHep.com - the global online resource for all aspects of gastroenterology, hepatology and endoscopy Profile of Roy Pounder

Home

News  
Journals
Review Articles
Slide Atlas
Video Clips
Online Books
Advanced Digestive Endoscopy
Classical Cases
Conference Diary
PubMed
International GH Links
USA GH Links
National GH Links
National GI Societies
Other Useful Links




Emails on Gastroenterology and Hepatology
the National AIDS Treatment Advocacy Project
Visit the gastroenterology section of the EUMS

News

Capsule endoscopy superior to push enteroscopy in GI bleeds

Capsule endoscopy is superior to push enteroscopy and small bowel barium radiography for diagnosing clinically significant small bowel pathology in gastrointestinal bleeding, reports November's American Journal of Gastroenterology.

News image

fiogf49gjkf04

Capsule endoscopy has a superior ability to examine the entire small bowel mucosa.

Therefore, it has broadened the diagnostic evaluation of patients with obscure gastrointestinal bleeding.

Published studies have revealed a numerically superior performance of capsule endoscopy.

Capsule endoscopy has a superior performance in determining a source of obscure gastrointestinal bleeding compared with other modalities.

However, due to small sample sizes, the overall magnitude of benefit is unknown.

Additionally, the types of lesions more likely to be found by capsule endoscopy versus alternate modalities are also unknown.

Dr Sharma Virender and colleagues evaluated the yield of small bowel findings with capsule endoscopy in obscure gastrointestinal bleeding.

The researchers compared these findings to other modalities using meta-analysis.

The research team performed a recursive literature search of prospective studies.

Incremental yield of capsule endoscopy for clinically significant findings is 30% with a number needed to treat of 3
American Journal of Gastroenterology

The studies included in the analysis compared the yield of capsule endoscopy to other modalities for obscure gastrointestinal bleeding.

Data on yield and types of lesions identified among various modalities were extracted, pooled, and analyzed.

The team calculated incremental yield and 95% confidence intervals of capsule endoscopy over comparative modalities.

A total of 14 studies with 396 participants compared the yield of capsule endoscopy with push enteroscopy for obscure gastrointestinal bleeding.

The researchers found that the yield for capsule endoscopy and push enteroscopy was 63% and 28%, respectively.

The yield for capsule endoscopy and push enteroscopy with clinically significant findings in 379 participants was 56% and 26%, respectively.

The team noted 3 studies with 88 participants that compared the yield of capsule endoscopy to small bowel barium radiography.

The yield for capsule endoscopy and small bowel barium radiography for any finding was 67% and 8%, respectively.

For clinically significant findings, the yield for capsule endoscopy and small bowel barium radiography for any finding was 42% and 6%, respectively.

The research team observed that the number needed to test to yield 1 additional clinically significant finding with capsule endoscopy over either modality was 3.

The team found the studies compared the yield of significant findings on capsule endoscopy to intraoperative enteroscopy, and computed tomography enteroclysis.

These studies also compared the yield of findings on capsule endoscopy to mesenteric angiogram, and small bowel magnetic resonance imaging.

The researchers noted that 10 of the 14 trials comparing capsule endoscopy with push enteroscopy classified the types of lesions found on examination.

Capsule endoscopy had a 36% yield for vascular lesions versus 20% for push enteroscopy, with an incremental yield of 16%.

The team observed inflammatory lesions in 11% with capsule endoscopy vs 2% with push enteroscopy, with an incremental yield of 9%.

There was no significant difference in the yield of tumors or ‘other' findings between capsule endoscopy and push enteroscopy.

Dr Virender's team concludes, “Capsule endoscopy is superior to push enteroscopy and small bowel barium radiography for diagnosing clinically significant small bowel pathology in patients with obscure gastrointestinal bleeding.”

“In study populations, the incremental yield of capsule endoscopy over push enteroscopy and small bowel barium radiography for clinically significant findings is 30% with a number needed to treat of 3.”

“This is primarily due to visualization of additional vascular and inflammatory lesions by capsule endoscopy.”

Am J Gastroenterol 2005: 100(11): 2407
01 November 2005

Go to top of page Email this page Email this page to a colleague

 17 January 2018 
“Weekend effect” in upper GI hemorrhage
 17 January 2018 
Gut dysbiosis and non-antibiotic prescription medications
 17 January 2018 
Reducing surgical infections in high-outlier colorectal unit
 16 January 2018 
Bundle of care in GI cancer surgery
 16 January 2018 
Anxiety about colonoscopy
 16 January 2018 
Thiopurines and colorectal neoplasia in IBD
 15 January 2018 
Risks of death after liver transplants for liver cancer
 15 January 2018 
Recent advances in hepatocellular carcinoma
 15 January 2018 
Ileostomy output using telemedicine
 12 January 2018 
Surveillance protocols after colorectal cancer resection
 12 January 2018 
Biologic therapy by pregnant women with IBD and infant vaccines
 12 January 2018 
Biologic therapies for IBD in the USA
 11 January 2018 
Genetic risk factors in GERD
 11 January 2018 
Predictor of colorectal adenoma
 11 January 2018 
Ectopic pregnancy in IBD 
 10 January 2018 
Fecal immunochemical tests for colorectal cancer screening
 10 January 2018 
Risk factors for advanced NAFLD
 10 January 2018 
Dyspepsia prevalence with gastroesophageal reflux–type symptoms
 09 January 2018 
Screening intervals for people with family histories of colorectal cancer
 09 January 2018 
Financial impact of colorectal cancer
 09 January 2018 
Current practice and future research in autoimmune hepatitis
 08 January 2018 
Improving prognosis in patients with primary sclerosing cholangitis
 08 January 2018 
Reliability of the IBD index
 08 January 2018 
Aprepitant and nausea with gastroparesis
 05 January 2018 
Autoimmune pancreatitis and IBD
 05 January 2018 
Primary nonresponse to infliximab therapy
 05 January 2018 
Anesthesia assistance in outpatient colonoscopy
 04 January 2018 
Dietary polyphenols in the etiology of IBD
 04 January 2018 
Yoga vs low-FODMAP in IBS
 04 January 2018 
Local esophageal food allergen injections in eosinophilic esophagitis
 03 January 2018 
Population health management for IBD
 03 January 2018 
GERD in asthma and COPD
 03 January 2018 
Critical research gaps in colorectal cancer
 22 December 2017 
Costs of extrahepatic manifestations of Hep C
 22 December 2017 
Cholera vaccine and risk of death in colorectal cancer
 22 December 2017 
Colonoscopy after colorectal cancer resection
 21 December 2017 
Human oral microbiome and pancreatic cancer risk
 21 December 2017 
Health management for IBD
 21 December 2017 
PPI and Alzheimer's disease
 20 December 2017 
Incidence of biopsy-verified celiac disease
 20 December 2017 
Osteoporotic fractures in Barrett's esophagus
 20 December 2017 
Management of abnormal liver blood tests
 19 December 2017 
Family burden of pediatric Crohn's in the USA
 19 December 2017 
Alcohol abstinence and alcoholic hepatitis
 19 December 2017 
Early readmission in IBD patients
 18 December 2017 
Colorectal cancer mortality with low-risk adenomas at colonoscopy
 18 December 2017 
Disease activity indices in celiac disease
 18 December 2017 
Smoking behaviour predicted the risk of surgery in Crohn's
 15 December 2017 
Molecular classification of Crohn's disease
 15 December 2017 
Medical cannabinoid legalization policy and vomiting
 15 December 2017 
Inflammatory diet pattern and colorectal cancer risk
 14 December 2017 
PPIs and gastric cancer after H.pylori eradication
 14 December 2017 
H. pylori eradication therapies in countries with clarithromycin resistance
 13 December 2017 
Disease severity in NAFLD
 13 December 2017 
Tryptophan metabolism and IBD activity
 12 December 2017 
Risk factors in undiagnosed cirrhosis
 12 December 2017 
Monitored anesthesia care for outpatient GI endoscopy
 12 December 2017 
High-risk colorectal cancer patients
 06 December 2017 
Reflux-induced chronic cough 
 06 December 2017 
Systemic inflammatory response syndrome in acute-on-chronic liver failure

Blackwell Publishing


GastroHep.com is a Blackwell Publishing registered trademark
© 2018 Wiley-Blackwell and GastroHep.com and contributors
Privacy Statement
Disclaimer
About Us