Help
Subscribe


All of GastroHep is now free access! - Click here to register Read For FREE - Our full range of review articles
GastroHep.com - the global online resource for all aspects of gastroenterology, hepatology and endoscopy
GastroHep.com - the global online resource for all aspects of gastroenterology, hepatology and endoscopy Profile of Guido Tytgat Profile of Pete Peterson Profile of Peter Cotton Profile of Roy Pounder

Home

News  
Journals
Review Articles
Slide Atlas
Video Clips
Online Books
Advanced Digestive Endoscopy
Classical Cases
Conference Diary
PubMed
International GH Links
USA GH Links
National GH Links
National GI Societies
Other Useful Links




Emails on Gastroenterology and Hepatology
the National AIDS Treatment Advocacy Project
Visit the gastroenterology section of the EUMS

News

Impact of race and ethnicity on IBD

The most recent issue of the American Journal of Gastroenterology shows that there are significant differences in IBD subtypes and serologic markers among racial/ ethnic groups with IBD in the United States.

News image

Inflammatory bowel disease (IBD) is now increasingly recognized in diverse ethnic populations.

In the United States, IBD among the minority populations, especially Mexican Americans, has not been extensively studied.

The are the known genetic influences that differ among the IBD subtypes, including ulcerative colitis and Crohn's disease.

Serologic markers may differentiate ulcerative colitis and Crohn's disease.

Serologic markers also differentiate perinuclear antineutrophilic cytoplasmic antibody and anti-Saccharomyces cerevisiae antibody in ulcerative colitis and Crohn's disease.

Dr Joseph Sellin and colleagues from Texas determined whether there were significant differences among racial or ethnic groups.

The investigators included 148 patients with IBD seen in a university gastroenterology practice between 1999 and 2003.

African Americans with Crohn's had a higher incidence of IBD-associated arthritis
The American Journal of Gastroenterology

The team reported that Whites comprised 40%, African Americans 37%, Mexican Americans 20%, and Asians 3% of the total IBD patients.

The investigators found that African Americans and Whites predominantly had Crohn's disease.

The team noted that Mexican Americans predominantly had ulcerative colitis.

There was no difference between African Americans when compared to whites in terms of intestinal manifestations of Crohn's disease.

The investigators also observed no difference between Mexican Americans compared to whites in terms of intestinal manifestations of ulcerative colitis.

However, African Americans with Crohn's disease had a significantly higher incidence of IBD-associated arthritis.

The team noted that African Americans with Crohn's had a higher incidence of ophthalmological manifestations, notably uveitis, compared to whites with Crohn's.

Among ulcerative colitis patients, in comparison to the Mexican Americans, whites had significantly higher incidences of joint symptoms and osteoporosis.

The investigative team noted that whites had a stronger family history of IBD and colorectal carcinoma compared to the other ethnic groups.

Perinuclear antineutrophilic cytoplasmic antibody served as a sensitive marker for ulcerative colitis among Mexican Americans.

All the Mexican American patients with ulcerative colitis tested had positive perinuclear antineutrophilic cytoplasmic antibody vs 40% of whites.

Dr Sellin's team concludes, “There are significant differences in IBD subtypes and serologic markers among racial/ ethnic groups with IBD in the United States.”

Am J Gastroenterol 2005: 100(10) 2254
26 September 2005

Go to top of page Email this page Email this page to a colleague

 17 April 2014

Advanced search
 17 April 2014 
Diabetes mellitus and acute pancreatitis
 17 April 2014 
Screening for low bone mineral density among ulcerative colitis
 17 April 2014 
Bowel cleansing for colonoscopy
 16 April 2014 
Evaluating pharmacologic agents in IBS
 16 April 2014 
Isotretinoin and IBD risk
 16 April 2014 
Mortality in bleeding Mallory-Weiss syndrome vs peptic ulcer bleeding
 15 April 2014 
Dietary fat and risk of IBD
 15 April 2014 
Quality of life in microscopic colitis
 15 April 2014 
New prognostic score for cirrhosis
 14 April 2014 
Changing liver cancer mortality rates in the United States
 14 April 2014 
Inflammatory sacroiliitis by MRI in IBD
 14 April 2014 

5-aminosalicylates in early pregnancy and congenital malformation risk

 11 April 2014 
H pylori resistance to antibiotics
 11 April 2014 
Predictors of corticosteroid treatment outcomes for ulcerative colitis
 11 April 2014 
Antibiotic combination therapy for ulcerative colitis
 10 April 2014 
Mortality in Crohn's disease
 10 April 2014 
Prophylaxis against venous thromboembolism in hospitalized ulcerative colitis
 10 April 2014 
Probiotic treatment and infant colic
 09 April 2014 
Preventing death in general intensive care
 09 April 2014 
Neoplasm risk after polypectomy
 09 April 2014 
Disclosure program and gastroenterology-related claims
 08 April 2014 

Regurgitation and health-related quality of life in GERD

 08 April 2014 
H. pylori resistance to antibiotics
 08 April 2014 
Management of chronic diarrhea
 07 April 2014 
Meat intake and liver cancer
 07 April 2014 
Gastrointestinal angiodysplastic lesions
 07 April 2014 
Adenoma detection and colorectal cancer risk
 04 April 2014 
Stool DNA tests for colorectal cancer
 04 April 2014 
PET-CT predicts outcome in colorectal liver metastases
 04 April 2014 

Prophylaxis of post-ERCP pancreatitis

 03 April 2014 
Management of esophageal or gastric variceal bleeding
 03 April 2014 
Exclusionary diets for IBD
 03 April 2014 
Mortality with chronic pancreatitis
 02 April 2014 
Disease course of early-onset pediatric IBD
 02 April 2014 
Risk of liver fibrosis progression in chronic hep B
 02 April 2014 
Colorectal cancer and patient survival
 01 April 2014 
Outcomes in patients with Hep C
 01 April 2014 
Diagnosis of functional dyspepsia
 01 April 2014 
Genetic risk factors for stenosis and infections in primary sclerosing cholangitis
 31 March 2014 
Diet-gene interactions and Crohn's
 31 March 2014 
Transjugular intrahepatic portosystemic stent-shunts in Budd–Chiari syndrome
 31 March 2014 
Hepatic decompensation in antiretroviral-treated patients
 28 March 2014 
Glucocorticoids and mortality after colorectal cancer surgery
 28 March 2014 
Long-term metformin use and gastric cancer risk
 28 March 2014 
Distance from a liver transplant center and survival
 27 March 2014 
Radiofrequency ablation vs endoscopy for Barrett's
 27 March 2014 
Omega-3 fatty acid and Crohn's disease
 27 March 2014 
Thromboembolism prophylaxis in IBD
 26 March 2014 
Disparities in evaluation of rectal bleeding
 26 March 2014 
Prediction of H. pylori status after endoscopy
 26 March 2014 
Fatigue and depression in IBD
 25 March 2014 
Depression risk in IBD
 25 March 2014 
Fecal incontinence in the USA
 25 March 2014 
Circulating gastrin and colorectal carcinoma risk
 24 March 2014 
Parental-rearing styles in IBS
 24 March 2014 
Endocannabinoid system in liver disease
 24 March 2014 
Maternal iron supplementation during pregnancy
 21 March 2014 
Eosinophilic esophagitis in the United States
 21 March 2014 
Chemoradiotherapy for anal cancer in HIV patients
 21 March 2014 
Diagnostic modalities in gastroenterology

Blackwell Publishing


GastroHep.com is a Blackwell Publishing registered trademark
© 2014 Wiley-Blackwell and GastroHep.com and contributors
Privacy Statement
Disclaimer
About Us