Help
Subscribe


GastroHep.com - the global online resource for all aspects of gastroenterology, hepatology and endoscopy

 23 January 2017

Advanced search
GastroHep.com - the global online resource for all aspects of gastroenterology, hepatology and endoscopy Profile of Roy Pounder

Home

News  
Journals
Review Articles
Slide Atlas
Video Clips
Online Books
Advanced Digestive Endoscopy
Classical Cases
Conference Diary
PubMed
International GH Links
USA GH Links
National GH Links
National GI Societies
Other Useful Links




Emails on Gastroenterology and Hepatology
the National AIDS Treatment Advocacy Project
Visit the gastroenterology section of the EUMS

News

Impact of race and ethnicity on IBD

The most recent issue of the American Journal of Gastroenterology shows that there are significant differences in IBD subtypes and serologic markers among racial/ ethnic groups with IBD in the United States.

News image

fiogf49gjkf04

Inflammatory bowel disease (IBD) is now increasingly recognized in diverse ethnic populations.

In the United States, IBD among the minority populations, especially Mexican Americans, has not been extensively studied.

The are the known genetic influences that differ among the IBD subtypes, including ulcerative colitis and Crohn's disease.

Serologic markers may differentiate ulcerative colitis and Crohn's disease.

Serologic markers also differentiate perinuclear antineutrophilic cytoplasmic antibody and anti-Saccharomyces cerevisiae antibody in ulcerative colitis and Crohn's disease.

Dr Joseph Sellin and colleagues from Texas determined whether there were significant differences among racial or ethnic groups.

The investigators included 148 patients with IBD seen in a university gastroenterology practice between 1999 and 2003.

African Americans with Crohn's had a higher incidence of IBD-associated arthritis
The American Journal of Gastroenterology

The team reported that Whites comprised 40%, African Americans 37%, Mexican Americans 20%, and Asians 3% of the total IBD patients.

The investigators found that African Americans and Whites predominantly had Crohn's disease.

The team noted that Mexican Americans predominantly had ulcerative colitis.

There was no difference between African Americans when compared to whites in terms of intestinal manifestations of Crohn's disease.

The investigators also observed no difference between Mexican Americans compared to whites in terms of intestinal manifestations of ulcerative colitis.

However, African Americans with Crohn's disease had a significantly higher incidence of IBD-associated arthritis.

The team noted that African Americans with Crohn's had a higher incidence of ophthalmological manifestations, notably uveitis, compared to whites with Crohn's.

Among ulcerative colitis patients, in comparison to the Mexican Americans, whites had significantly higher incidences of joint symptoms and osteoporosis.

The investigative team noted that whites had a stronger family history of IBD and colorectal carcinoma compared to the other ethnic groups.

Perinuclear antineutrophilic cytoplasmic antibody served as a sensitive marker for ulcerative colitis among Mexican Americans.

All the Mexican American patients with ulcerative colitis tested had positive perinuclear antineutrophilic cytoplasmic antibody vs 40% of whites.

Dr Sellin's team concludes, “There are significant differences in IBD subtypes and serologic markers among racial/ ethnic groups with IBD in the United States.”

Am J Gastroenterol 2005: 100(10) 2254
26 September 2005

Go to top of page Email this page Email this page to a colleague

 23 January 2017 
Fatigue in IBD after diagnosis
 23 January 2017 
Diagnosis of pancreatic cancer
 23 January 2017 
Care pathway for anemia in IBD 
 20 January 2017 
Abnormalities in functional dyspepsia
 20 January 2017 
Predictors of small bowel Crohn's in capsule endoscopy
 20 January 2017 
Stool output after a meal
 19 January 2017 
Prediction of chronic liver disease mortality
 19 January 2017 
Infliximab treatment algorithm in IBD
 19 January 2017 
Radiation exposure in IBD and IBS 
 18 January 2017 
Helicobacter pylori eradication and insulin resistance
 18 January 2017 
Hormone levels and NAFLD severity
 18 January 2017 
Measure of GERD
 17 January 2017 
Pediatric-onset Crohn's disease
 17 January 2017 
Biologic drugs and extraintestinal manifestations in IBD
 17 January 2017 
Colorectal cancer prevention among Medicare beneficiaries
 16 January 2017 
HCV eradication in cirrhosis
 16 January 2017 
Thyroid and primary biliary cholangitis
 16 January 2017 
Sarcopenia and severe liver fibrosis
 13 January 2017 
Early monocytopenia in paracetamol-induced liver failure
 13 January 2017 
Anti-TNF discontinuation in patients with IBD
 13 January 2017 
Isolated colonic Crohn's disease
 12 January 2017 
Providing relief for chronic constipation
 12 January 2017 
Internet-delivered therapy for adolescents with IBS
 12 January 2017 
NAFLD and coronary artery calcium score
 11 January 2017 
Fatigue in IBD
 11 January 2017 
Pancreatic cancer risk with asthma and nasal allergies
 11 January 2017 
PPIs and bone strength and structure
 10 January 2017 
Colorectal cancer risk in serrated polyposis syndrome
 10 January 2017 
Evaluation of abnormal liver chemistries
 10 January 2017 
Pelvic physiotherapy in functional constipation
 09 January 2017 
Intestinal microbiota and IBS
 09 January 2017 
Helicobacter and Campylobacter in IBD
 09 January 2017 
Diagnosis of microscopic colitis
 06 January 2017 
Recommendations on colorectal cancer screening 
 06 January 2017 
Colorectal cancer susceptibility gene variants
 06 January 2017 
Thiopurine-induced hepatotoxicity in IBD
 05 January 2017 
Histological index for ulcerative colitis
 05 January 2017 
Crohn's disease after total colectomy with permanent ileostomy
 05 January 2017 
Celiac disease screening in IBS
 04 January 2017 
Serrated colorectal polyps risk factors
 04 January 2017 
Score to predict eosinophilic esophagitis
 04 January 2017 
Platelet transfusion for gastrointestinal bleeding
 03 January 2017 
Pelvic physiotherapy for functional constipation in children
 03 January 2017 
Tumor necrosis factor antagonists in IBD
 03 January 2017 
Mesenchymal stromal cell therapy for IBD
 22 December 2016 
Happy holidays!
 21 December 2016 
Pharmacotherapy for NAFLD
 21 December 2016 
Predicting disease activity in eosinophilic esophagitis
 21 December 2016 
Breath Testing for Barrett’s esophagus
 20 December 2016 
H. pylori on the ethnic distribution of Barrett's metaplasia
 20 December 2016 
Prognostic biomarker in colorectal cancer
 20 December 2016 
Online health information for colorectal cancer screening
 19 December 2016 
Risk of tuberculosis in IBD
 19 December 2016 
Risk of complications of percutaneous liver biopsy
 19 December 2016 
Hospital research and colorectal cancer survival
 16 December 2016 
Predicting organ failure in acute pancreatitis
 16 December 2016 
Mortality rates for major causes of death
 16 December 2016 
Non-invasive genomic biomarkers for colorectal cancer
 15 December 2016 
Adjuvant chemotherapy use varies for advance colon cancer
 15 December 2016 
Histological index for ulcerative colitis

Blackwell Publishing


GastroHep.com is a Blackwell Publishing registered trademark
© 2017 Wiley-Blackwell and GastroHep.com and contributors
Privacy Statement
Disclaimer
About Us