Help
Subscribe


Submit Videos to GastroHep Read For FREE - Our full range of review articles
GastroHep.com - the global online resource for all aspects of gastroenterology, hepatology and endoscopy
GastroHep.com - the global online resource for all aspects of gastroenterology, hepatology and endoscopy Profile of Guido Tytgat Profile of Pete Peterson Profile of Peter Cotton Profile of Roy Pounder

Home

News  
Journals
Review Articles
Slide Atlas
Video Clips
Online Books
Advanced Digestive Endoscopy
Classical Cases
Conference Diary
PubMed
International GH Links
USA GH Links
National GH Links
National GI Societies
Other Useful Links




Emails on Gastroenterology and Hepatology
the National AIDS Treatment Advocacy Project
Visit the gastroenterology section of the EUMS

News

Unified system of naming Hep C virus genotypes

The latest issue of Hepatology reports that a framework by which the Hepatitis C databases provides access to data on the virus, will internationally coordinate the assignment of new genotypes and subtypes in the future.

News image

International standardization and coordination of the nomenclature of variants of Hepatitis C virus is increasingly needed.

More is discovered about the scale of Hepatitis C-related liver disease and important biological and antigenic differences that exist between variants.

Dr Peter Simmonds and a colleagues expert in the field of Hepatitis C genetic variability, met to re-examine the status of HCV genotype nomenclature.

The researchers aimed to resolve conflicting genotype or subtype names among described variants of Hepatitis C.

The team also planned to draw up revised criteria for the assignment of new genotypes as they are discovered in the future.

Hep C will be classified into 6 genotypes, representing the 6 genetic groups
Hepatology

The researchers examined the Hepatitis Virus Database from Japan, the Hepatitis C virus database from France, and Los Alamos in the USA.

A listing of all classified variants of Hepatitis C incorporates a number of agreed genotype and subtype name reassignments to create consistency in nomenclature.

The paper also contains consensus proposals for the classification of new variants into genotypes and subtypes.

The researchers working on the paper recognize and incorporate new knowledge of Hepatitis C genetic diversity and epidemiology.

The team made a proposal that Hepatitis C variants be classified into 6 genotypes, representing the 6 genetic groups defined by phylogenetic analysis.

Subtype name assignment will be either confirmed or provisional, depending on the availability of complete or partial nucleotide sequence data.

The team plan to leave subtype name assignment unassigned where fewer than 3 examples of a new subtype have been described.

Dr Simmonds' team concludes, “These proposals provide the framework by which the Hepatitis C databases store and provide access to data on the virus."

"The framework will internationally coordinate the assignment of new genotypes and subtypes in the future.”

Hepatol 2005: 42(4): 962-73
26 September 2005

Go to top of page Email this page Email this page to a colleague

 27 January 2015

Advanced search
 27 January 2015 
Psychological distress and fecal composition in IBS
 27 January 2015 
Risk of upper GI cancers in GERD
 27 January 2015 
Outcomes for liver transplantation
 26 January 2015 
Antidepressants and GERD
 26 January 2015 
Breath analysis for IBD
 26 January 2015 
Fecal microbiota transplantation
 23 January 2015 
Liver transplant outcomes
 23 January 2015 
Breath analysis in IBD
 23 January 2015 
Fecal microbiota transplantation
 22 January 2015 
NASH and lipid improvements
 22 January 2015 
NAFLD and NASH with psoriasis
 22 January 2015 
Predicting outcomes in HCV-related advanced liver disease
 21 January 2015 
Colon capsule versus CT colonography
 21 January 2015 
Barrett's esophagus screening in the community
 21 January 2015 
Portal vein obstruction
 20 January 2015 
Modulating mucosal damage in Crohn's
 20 January 2015 
Novel techniques for Barrett's screening
 20 January 2015 
Food intolerance
 19 January 2015 
Treatment of fecal incontinence
 19 January 2015 
Hepatic cyst infection
 19 January 2015 
Risk of IBS among relatives
 16 January 2015 
Colorectal cancer screening uptake
 16 January 2015 
NAFLD and NASH in patients with psoriasis
 16 January 2015 
Fecal incontinence
 15 January 2015 
Coffee intake and liver disease
 15 January 2015 
NAFLD in primary care practice
 15 January 2015 
Management of univestigated dyspepsia
 14 January 2015 
Missed colorectal cancers after colonoscopy with polypectomy
 14 January 2015 
Inflixmab response in Crohn's
 14 January 2015 
Statins and liver injury in chronic liver disease
 13 January 2015 
Cytomegalovirus in IBD
 13 January 2015 
Helicobacter-negative gastritis
 13 January 2015 
Hep B vaccine in IBD
 12 January 2015 
Survival in Hep B virus-related hepatocellular carcinoma
 12 January 2015 
Relapse of Crohn's disease after surgery
 12 January 2015 
Late liver metastases of colorectal cancer
 09 January 2015 
Fecal microbiota transplantation for refractory Crohn's
 09 January 2015 
Hypercoagulability after liver resection
 09 January 2015 
Naps and gastroesophageal reflux vs nocturnal sleep
 08 January 2015 
Post-infectious functional dyspepsia
 08 January 2015 
Diagnosis of liver iron overload
 08 January 2015 
Digestive tract damage in Crohn's disease
 07 January 2015 
Early-onset colorectal cancer
 07 January 2015 
SSRIs for noncardiac chest pain
 07 January 2015 
SSRIs and upper GI bleeds
 06 January 2015 
Detection of inflammation in Crohn's
 06 January 2015 
Leptin and early-onset extreme obesity
 06 January 2015 
Goals of IBD treatment
 19 December 2014 
Thiopurine treatment and colectomy in ulcerative colitis
 19 December 2014 
Idiopathic inflammatory demyelinating disease in IBD
 19 December 2014 
Colorectal cancer risk for first-degree relatives
 18 December 2014 
Vitamin D and sustained virologic response in HCV
 18 December 2014 
Factor for treatment in IBS
 18 December 2014 
Assessment of Crohn's disease activity
 17 December 2014 
Remission from hepatic encephalopathy with rifaximin
 17 December 2014 
Colonic adenoma recurrence after endoscopic resection
 17 December 2014 
Non-invasive measures of fatty liver
 16 December 2014 
Diagnostic tool for dysplasia in Barrett's
 16 December 2014 
Screening esophagus during routine US
 16 December 2014 
Therapeutic targets in IBD

Blackwell Publishing


GastroHep.com is a Blackwell Publishing registered trademark
© 2015 Wiley-Blackwell and GastroHep.com and contributors
Privacy Statement
Disclaimer
About Us