One study of 115 patients found that anti-HP therapy could tackle some pre-cancerous conditions found in the stomach.
Researchers, led by Toshifumi Ohkusa of Tokyo Medical and Dental University, Japan, reported that gastric mucosa pathology improved in most patients when Helicobacter pylori was successfully eradicated. Improvements in intestinal metaplasia were seen in 28 out of 48 patients.
"In the year after successful HP eradication, pre-cancerous lesions improved in most patients," they write.
But a second study found that HP therapy did not improve the symptoms of dyspepsia where the problem was not caused by ulcers or GI reflux.
| In meta-analysis, HP eradication does not impact the incidence of dyspepsia.|
| Annals of Internal Medicine |
Researchers led by Dr Loren Laine of the University of Southern California, Los Angeles, USA, studied the results of trials of HP therapy on patients who complained of dyspepsia and who had diagnosed HP infection.
The meta-analysis showed that curing HP infection made no difference to the incidence of dyspepsia.
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