Help
Subscribe


GastroHep.com - the global online resource for all aspects of gastroenterology, hepatology and endoscopy

 23 February 2018

Advanced search
GastroHep.com - the global online resource for all aspects of gastroenterology, hepatology and endoscopy Profile of Roy Pounder

Home

News  
Journals
Review Articles
Slide Atlas
Video Clips
Online Books
Advanced Digestive Endoscopy
Classical Cases
Conference Diary
PubMed
International GH Links
USA GH Links
National GH Links
National GI Societies
Other Useful Links




Emails on Gastroenterology and Hepatology
the National AIDS Treatment Advocacy Project
Visit the gastroenterology section of the EUMS

News

Hepatitis A in the USA declines in vaccination era

Following the implementation of routine Hepatitis A vaccination of children, infection rates have declined to historic lows, accompanied by substantial changes in the epidemiologic profile, reports the latest issue of the Journal of the American Medical Association.

News image

fiogf49gjkf04

In the United States, Hepatitis A is a frequently reported vaccine-preventable disease.

Vaccination has been recommended for persons at increased risk since 1996.

In 1999, it was recommended that children living in 11 states with the highest incidence of Hepatitis A be routinely vaccinated.

It was also recommended that children living in 6 additional states, with incidence above the national average, be considered for routine vaccination.

Dr Annemarie Wasley and colleagues assessed the impact of the current vaccination strategy.

The research team evaluated trends in reported cases of Hepatitis A since implementation.

Hep A declined 88% in vaccinating states compared with 53% elsewhere
Journal of the American Medical Association

The team conducted a longitudinal analysis of characteristics of cases of Hepatitis A.

The researchers included all cases reported in the United States since 1990 to the National Notifiable Diseases Surveillance System.

The main outcome measure was the incidence rates of reported cases of Hepatitis A.

Incidence rates in 2003 were compared with those for the prevaccination baseline period from 1990 to 1997.

The researchers also compared incidence rates in the 17 states in which children should be routinely vaccinated or are considered for routine vaccination.

Incidence rates in vaccinating states were also compared with nonvaccinating states, where there is no recommendation for statewide vaccination of children.

The team found that between the baseline period and 2003, overall Hepatitis A rates declined 76%, significantly lower than previous nadirs in 1983 and 1992.

The researchers noted that the rate in vaccinating states declined 88% compared with 53% elsewhere.

In 2003, the team observed that cases from vaccinating states accounted for 33% of the national total versus 65% during the baseline period.

Declines were greater among children aged 2 to 18 years than among persons older than age 18 years.

The researchers found that the proportion of cases in children dropped from 35% to 19%.

Since 2001, the team noted that rates in adults have been higher than among children, with the highest rates now among men aged 25 through 39 years.

Dr Wasley's team concludes, “Following implementation of routine Hepatitis A vaccination of children, Hepatitis A rates have declined to historic lows.”

“This decline is accompanied by substantial changes in the epidemiologic profile.”

“Greater decreases in the age groups and regions where routine vaccination of children is recommended likely reflect the results of implementation of this novel vaccination strategy.”

“Continued monitoring is needed to verify that implementation continues to proceed and that low rates are sustained. “

JAMA 2005: 294(2): 194-201
18 July 2005

Go to top of page Email this page Email this page to a colleague

 23 February 2018 
Patients on antithrombotic agents undergoing emergency and elective endoscopy
 23 February 2018 
Heavy metals on a gluten-free diet
 23 February 2018 
MRI and NAFLD
 22 February 2018 
Outcomes with Crohn’s after infliximab withdrawal
 22 February 2018 
Elderly onset of IBD

 22 February 2018 
Autophagy enhancers
 21 February 2018 
Management of hemorrhoids in the USA
 21 February 2018 
Adalimumab and infliximab in biologic-naïve Crohn's
 21 February 2018 
Cystic fibrosis and colorectal cancer
 20 February 2018 
Complications and surveillance colonoscopies
 20 February 2018 
Treatment algorithm for polyp cancers
 20 February 2018 
Predictors of postoperative infection in Crohn's
 19 February 2018 
Screening colonoscopy in the right and left colon
 19 February 2018 
NAFLD prevalence in the USA
 19 February 2018 
Fructans in children with IBS

 16 February 2018 
Inflammatory bowel diseases are global diseases
 16 February 2018 
Undetected celiac in the elderly
 16 February 2018 
Fructans induce non-celiac gluten sensitivity
 15 February 2018 
NSAIDS and GI damage
 15 February 2018 
Oral direct-acting antiviral treatment for Hep C virus genotype 1
 15 February 2018 
Primary vs secondary surgery for the presence of lymph node metastasis
 14 February 2018 
Predicting adenoma detection rate
 14 February 2018 
Normal bowel frequency characterization in the USA 
 13 February 2018 
Personalising treatment options for IBS
 13 February 2018 
Prebiotics improve endothelial dysfunction
 13 February 2018 
Diagnostic criteria for a Rome IV functional gastrointestinal disorders
 12 February 2018 
Visceral hypersensitivity and functional GI disorders
 12 February 2018 
Depression and aggressive IBD
 12 February 2018 
Variability in interpretation of endoscopic findings impacts patient management
 09 February 2018 
Treatment of choice for anastomotic stricture in IBD
 09 February 2018 
PRO measurement information system 
 09 February 2018 
Overall disease severity indices for IBD
 08 February 2018 
Prediction of endoscopically active disease

 08 February 2018 
Steroid-refractory acute severe ulcerative colitis
 08 February 2018 
Decision aid used by IBD patients
 07 February 2018 
Ursodeoxycholic acid combined with bezafibrate for itching
 07 February 2018 
Change in microbiome in gastritis vs gastric carcinoma
 07 February 2018 
Colorectal cancer and primary sclerosing cholangitis-IBD
 06 February 2018 
Risk of death after liver transplantation
 06 February 2018 
Crohn’s disease vs refractory pouchitis
 06 February 2018 
Support for functional dyspepsia symptom diary
 05 February 2018 
Helicobacter spp influence on GI tract 
 05 February 2018 
No link found between severe reflux and all-cause mortality 
 05 February 2018 
Psychological distress in PPI non-responders
 02 February 2018 
Assessing psychosexual impact of IBD
 02 February 2018 
Decrease in overall mortality with cholera vaccination
 02 February 2018 
Diagnostic performance of fecal immunochemical tests
 01 February 2018 
Screening frequency with family histories of colorectal cancer
 01 February 2018 
IBD and sport participation
 01 February 2018 
Life with a stoma 
 31 January 2018 
Aprepitant and gastroparesis 
 31 January 2018 
Anesthesia risk in colonoscopy
 31 January 2018 
GED-0301 for Crohn's Disease
 30 January 2018 
Intestinal dysbiosis and allergic diseases in infants
 30 January 2018 
Fructans and IBS symptoms in children
 29 January 2018 
Dosing calculator for therapy optimization in IBD
 29 January 2018 
Glecaprevir–pibrentasvir for in HCV
 29 January 2018 
Food allergen injections in eosinophilic esophagitis
 29 January 2018 
Reliability of the IBD index
 26 January 2018 
Tofacitinib vs biological therapies for ulcerative colitis

Blackwell Publishing


GastroHep.com is a Blackwell Publishing registered trademark
© 2018 Wiley-Blackwell and GastroHep.com and contributors
Privacy Statement
Disclaimer
About Us