Functional outcome and quality of life in older patients undergoing ileal pouch-anal anastomosis for ulcerative colitis or familial adenomatous polyposis have been incompletely studied.
Dr Jennifer Chapman and colleagues from Minnesota considered how age of the patient at the time of surgery influences functional outcome and quality of life after ileal pouch-anal anastomosis.
The research team studied 2000 patients who underwent ileal pouch-anal anastomosis between 1981 and 2000.
The team grouped the patients by age at operation where 1688 were grouped as 45 years or younger.
|Pouch failure rate for patients older than 55 years is 2% at 10 years|
|Archives of Surgery|
Other groupings included 249 patients between 46 and 55 years, and 65 patients as older than 55 years.
The team reported that the mean age of the patients was 34 years with a follow-up of 10 years, and a follow-up of 8 years for patients older that 55 years.
Postoperative complications, function, and quality of life were assessed with a questionnaire administered annually.
The researchers found that the pouch failure rate for patients older than 55 years was 2% at 10 years.
No statistically significant difference in pouch failure between age groups was observed by the team.
Overall, the researchers noted that frequent daytime and nighttime incontinence, respectively, occurred in 6% and 13% of the patients at 10 years.
The researcher team observed that incontinence was more common in older patients.
Quality of life as assessed by social activities, work, travel, sexual activity, family relationships, and sports and recreation was not different among age groups.
The team noted that most patients felt that their condition had improved or that they had no restrictions after ileal pouch-anal anastomosis.
Dr Chapman's team concludes, “Postoperative complications after surgery seem to be unrelated to age at the time of surgery.”
“Although incontinence may occur more frequently in older patients, ileal pouch-anal anastomosis does not adversely affect quality of life in patients older than 55 years.”