Several case reports and series report an association between celiac disease and inflammatory bowel disease (IBD).
However, there is no current data assessing this association.
Dr Yang studied the occurrence of these conditions in a cohort of patients with celiac disease seen at a referral center.
|The prevalence rate ratio for ulcerative colitis is 4 and for Crohn's disease 9|
|Inflammatory Bowel Disease|
The researchers analyzed a database of patients with celiac disease seen between 1981 and 2002 including only biopsy-proven adults.
The research team identified patients who had endoscopic and pathologic evidence of IBD and reviewed their pathology.
The team determined age- and sex-adjusted prevalence rate ratios by comparing results with population-based prevalence data.
The investigative team identified IBD in 10 among 455 patients with celiac disease, of which 5 had ulcerative colitis and 5 had Crohn's disease.
In addition, the team reported that this represented an age- and sex-adjusted prevalence rate ratio for ulcerative colitis of 4 and for Crohn's disease of 9.
Dr Yang concluded, “Within our cohort of patients with celiac disease, IBD was significantly more common than in the general population.”