Limited information is available about anxiety, depression and psychotropic medication use in patients referred for gastrointestinal endoscopy.
Dr Kerkhoven and colleagues from the Netherlands determined the association of anxiety and depression with endoscopic findings in a representative sample of patients with persistent gastrointestinal symptoms prior to endoscopy.
The researchers included patients referred to the hospital for endoscopy between 2002 and 2004.
The research team obtained information about endoscopic diagnoses from medical files and asked patients to score anxiety and depression on the Hospital Anxiety and Depression Scale 2 weeks prior to endoscopy.
The team studied a total of 1298 subjects, of which 600 had upper gastrointestinal endoscopies and 698 had lower gastrointestinal endoscopies.
| Psychotropic agent use in patients with organic abnormality was 42% versus 8% without an organic abnormality|
|Alimentary Pharmacology & Therapeutics|
The investigators found that patients referred for upper gastrointestinal endoscopy used most psychotropic agents, with a prevalence of 24%.
In patients with an organic abnormality, the use of psychotropic agents was 42% as compared to patients without an organic abnormality with a use of 8%.
The investigative team also noted that patients with colonic polyps were more anxious and depressed than other patients referred for lower gastrointestinal endoscopy.
Dr Kerkhoven’s team concluded, “There is no difference in anxiety or depression between patients with and without organic abnormalities at endoscopy.”
“Patients with colonic polyps are more anxious and depressed than other patients referred for lower gastrointestinal endoscopy.”
“Psychotropic medication use is highest among patients with an organic abnormality in the proximal gastrointestinal tract.”