Researchers evaluated whether white wine disturbs esophageal peristalsis and acid clearance and reported their findings in December's Scandinavian Journal of Gastroenterology.
12 healthy volunteers received either 300ml white wine (8% vol/vol), or an ethanol solution (8% vol/vol), or tap water, together with a standardized meal in a random order.
|Scan J Gastroent 2000; 35 (12): 1255-9
|Scandinavian Journal of Gastroenterology|
Acid clearance was tested by instillation of 15 ml 0.1 NHCl into the distal esophagus. The number of dry swallows every 30 seconds were counted until pH rose above 5.
5 wet swallows (5 ml) were applied to test primary peristalsis, and 5 insufflations of 20 ml of air were performed to test secondary peristalsis. Each test was done immediately after and 60 min after ingestion of the beverages.
The team found that a significantly higher number of swallows were needed to clear the esophagus immediately after ingestion of wine (12 vs. 8 for ethanol and 7 for water) due to an increase in the frequency of failed, simultaneous, and low-amplitude contractions.
After ingestion of white wine, the frequency of triggered secondary contractions was decreased to 70% of that for ethanol and water. The latency between air injection and onset of secondary peristalsis was also prolonged to 9 seconds, compared to 7 for ethanol and 6 for water.
Wet swallow induced primary peristalsis was not influenced by wine. No significant differences in the measured parameters were seen 60 min after ingestion of the three beverages.
Researcher C. Pehl concluded on behalf of the group, "White wine temporarily disturbs esophageal clearance, due to a disturbance of triggering secondary peristalsis and due to an increase in ineffective contractions.
"The ethanol content alone is not responsible for the effects of white wine on esophageal peristalsis and acid clearance."