Surgical site infections and disruption of sutured tissue are frequent complications following surgery.
Dr Sorensen and colleagues assessed risk factors predictive of tissue and wound complications in open gastrointestinal surgery.
The research team recorded and validated data from 4855 unselected patients undergoing open gastrointestinal surgery from 1995 through 1998 in a clinical database.
The researchers included variables from the database related to patient history, preoperative clinical condition, operative findings and severity, and the surgeon's training.
The team then assessed the variables predictive of surgical site infection and dehiscence of sutured tissue within 30 days after surgery by multiple logistic regression analysis.
The investigative team found that following elective operation, the incidence of tissue and wound complications was 6% compared with 16% in emergency surgery.
| Tissue and wound complications resulted in a 3 fold higher risk of reoperation|
|Annals of Surgery|
Tissue and wound complications resulted in prolonged hospitalization in 50% of the patients and a 3 fold higher risk of reoperation but not increased mortality.
The investigators reported that factors associated with complications following elective operations were smoking, comorbidity, and perioperative blood loss.
In addition, the team noted that following emergency operations, male gender, peritonitis, and multiple operations were predictors of complications.
The researchers concluded that irrespective of elective or emergency surgery, the type of operation was a predictor of complications.
Dr Sorensen concludes, “Factors known to affect the process of tissue and wound healing are independently associated with tissue and wound complications following gastrointestinal surgery.”