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News

High prevalence of esophageal disorders with recurrent chest pain

An association between esophageal disorders and dysphagia coexistence as well as a high prevalence of esophageal disorders exists in patients with recurrent chest pain, reports this month's Diseases of the Esophagus.

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Dr Manterola and colleagues from Chile determined the prevalence of esophageal disorders associated with recurrent chest pain and the utility of esophageal functional tests in the study of these patients.

The research team conducted a cross-sectional study was conducted at Hospital ClÌnico de La Frontera, Chile.

The team studies 123 patients with recurrent chest pain using esophageal manometry, edrophonium stimulation and 24 hour pH monitoring.

The researchers considered the performance of esophageal functional tests acceptable when they were capable of finding esophageal disorders.

To state the probability that recurrent chest pain had an esophageal origin, the investigators classified patients according to whether their pain had a probable, possible or unlikely esophageal origin.

The prevalence of esophageal disorders was determined according to diagnoses obtained after applying esophageal functional tests.

The researchers performed multivariate analysis to examine the association between the esophageal origin of recurrent chest pain and esophageal disorders.

In 38% of patients with recurrent chest pain, the pain was probably of esophageal origin
Diseases of the Esophagus

Rates of correct diagnosis of 66%, 57% and 32% was verified for 24 hour pH monitoring, esophageal manometry and edrophonium stimulation, respectively.

The team also found that in 38% of patients with recurrent chest pain, the pain was probably of esophageal origin, in 42% there was a possible esophageal origin and in 20% an unlikely esophageal origin.

In addition, the researchers verified a 45% prevalence of gastroesophageal reflux disease (GERD), 27% of GERD with secondary esophageal motor dysfunction and 9% of pure esophageal motor dysfunction.

Dr Manterola’s team concludes, “The multivariate analysis allowed us to verify the association between the probability of esophageal origin of recurrent chest pain, the variables recurrent chest pain duration, esophagitis and dysphagia coexistence.”

“A statistically significant association between esophageal disorders and dysphagia coexistence was established and a high prevalence of esophageal disorders was identified in patients with recurrent chest pain.”

Dis Esophagus 2005: 17(4): 285
07 April 2005

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