Endoscopic ultrasound-guided fine-needle aspiration of pancreatic cysts is considered safe, however, data are conflicting regarding complication rates.
Dr Lee and colleagues studied the complication rate of endoscopic ultrasound-guided pancreatic cyst aspiration and predictors of these complications.
|No patient or cyst characteristics appear to be predictive of adverse events|
|Clinical Gastroenterology and Hepatology|
The researchers reviewed the results of pancreatic cyst endoscopic ultrasound-guided fine-needle aspiration at 2 academic institutions from 1996 to 2003.
The research team evaluated a total of 603 patients with 651 pancreatic cysts.
Complications were identified by the team from clinic, emergency department, and discharge notes, and laboratory and radiologic data.
The team collected data including cyst size, location, septations, diagnosis, number of passes, needle size, status as inpatient or outpatient, performance of same-day endoscopic retrograde cholangiopancreatography, and use of prophylactic antibiotics.
The investigators identified complications in 13 patients, of which 6 patients had pancreatitis, 4 patients had abdominal pain, 1 patient had a retroperitoneal bleed, 1 patient had an infection, and 1 patient had bradycardia.
12 patients required hospitalization, with an average length of stay of 4 days.
The researchers found that type of cyst, size, presence of septations or mass, and same-day endoscopic retrograde cholangiopancreatography were not predictors of complications.
Dr Lee's team concludes, “Endoscopic ultrasound-guided pancreatic cyst aspiration carries a low complication rate similar to that reported for solid pancreatic lesions.”
“No patient or cyst characteristics appear to be predictive of adverse events."