The diagnostic yield of capsule endoscopy depends on the quality of visualization of the small-bowel wall and complete passage through the small bowel.
Dr Bauerfeind and colleagues from Zurich, Switzerland undertook a study in order to examine the effect of bowel preparation on the volume of intestinal content and on small-bowel transit.
The research team enrolled a total of 61 consecutive patients (34 men, 27 women; mean age 56 years, range 17-88 years) in the study.
Although not randomized, 33 patients received a bowel preparation, and 28 had no preparation.
3 Investigators, unaware of whether the patient had undergone bowel preparation, evaluated participants' gastric emptying, small-bowel transit time, overall preparation assessment, and bowel-wall visualization.
|Capsule reached the cecum in 97% of patients in the bowel-preparation group vs 76% in the nonpreparation group|
The researchers found that small-bowel transit time was significantly shorter in patients with bowel preparation (median 213 minutes) than in those without preparation (median 253 minutes).
The research team noted that the capsule reached the cecum in 97% of patients in the bowel-preparation group, compared with 76% in the nonpreparation group.
In addition, the researchers found that bowel preparation improved the quality of visualization significantly and this effect was more pronounced in the distal small bowel.
Dr Bauerfeind concluded, "This study demonstrated that bowel preparation accelerates small-bowel capsule transit and leads to a higher rate of complete capsule endoscopy."
"Visualization of the small bowel was improved by bowel preparation."
"Bowel preparation before capsule endoscopy is recommended."