Help
Subscribe


GastroHep.com - the global online resource for all aspects of gastroenterology, hepatology and endoscopy

 22 April 2018

Advanced search
GastroHep.com - the global online resource for all aspects of gastroenterology, hepatology and endoscopy Profile of Roy Pounder

Home

News  
Journals
Review Articles
Slide Atlas
Video Clips
Online Books
Advanced Digestive Endoscopy
Classical Cases
Conference Diary
PubMed
International GH Links
USA GH Links
National GH Links
National GI Societies
Other Useful Links




Emails on Gastroenterology and Hepatology
the National AIDS Treatment Advocacy Project
Visit the gastroenterology section of the EUMS

News

Lifestyle related risk factors in the aetiology of GERD

Smoking and a high dietary salt intake significantly increase the risk of acid reflux, but tea and alcohol, often thought to be culprits, seem to have little impact, finds a large study in Gut.

News image

fiogf49gjkf04

Acid reflux, also known as gastro-oesophageal reflux (GERD), is common and one of the most frequent causes of indigestion.

Symptoms arise when stomach acid flows back into the oesophagus or gullet - often as far as the mouth - usually as a result of a weakened muscle at the bottom of the gullet.

Typical symptoms include heartburn, excessive belching, and even respiratory problems.

Researchers from Stockholm, Norway undertook a study to evaluate the lifestyle-related risks associated with GERD.

The research group based their work on 47,556 people, who had previously taken part in two major public health surveys in Nord-Trondelag, a county in Norway.

The first survey, involving more than 74,000 people, was conducted between 1984 and 1986; the second spanned the period 1995 to 1997 and included more than 65,000 people.

In the second survey, researchers identified 3153 people who complained of severe heartburn and reflux into the mouth within the preceding 12 months as having acid reflux. Their average age was 52.

The research team quizzed the participants about their lifestyles, including diet, exercise, alcohol intake, and tobacco habit.

The researchers then compared their responses with those from 40,210 people without symptoms, whose average age was 48.

Heavy coffee drinkers (around 7 cups a day) were 40% less likely to develop acid reflux than those who drank 1 or fewer cups a day
Gut

The research group found that lifestyle was strongly linked to acid reflux symptoms.

People who had smoked every day for more than 20 years were 70% more likely to have acid reflux than non-smokers.

In addition, the researchers noted that salt intake proved to be as great a risk factor.

Participants who routinely added salt to meals were 70% more likely to have acid reflux than those who did not.

Salted meat or fish eaten three or more times a week ensured participants were 50% more likely to have acid reflux than those who never ate these foods.

The investigators found that some lifestyle factors seemed to confer protection.

Regular consumption of high fibre brown bread and 30 minutes of strenuous exercise at least once a week both halved the risk of developing acid reflux.

The researchers suggested that the protective capacity of dietary fibre might lie in the fact that it mops up large amounts of nitric oxide in the stomach, produced from nitrites in the diet, say the authors.

Nitric oxide relaxes the muscle at the bottom of the gullet, so promoting reflux.

Surprisingly, the researchers found that heavy coffee drinkers (around 7 cups a day) were also around 40% less likely to develop acid reflux than those who drank one or fewer cups a day.

However, the authors point out that people with acid reflux might abstain from coffee drinking, which could potentially skew the results.

Neither tea nor alcohol, irrespective of the quantities drunk, had any impact on risk.

Gut; 2004: 53: 1730-5
12 November 2004

Go to top of page Email this page Email this page to a colleague

 20 April 2018 
Obesity and physical activity in diverticulosis
 20 April 2018 
Worldwide H.pylori prevalence
 20 April 2018 
Adalimumab with azathioprine in Crohn's
 19 April 2018 
Fibrosis in patients with chronic hepatitis B
 19 April 2018 
c-Myc expression and pancreatic cancer
 19 April 2018 
Olmesartan prescription in the USA
 18 April 2018 
Online tool predicts bowel dysfunction severity prior to anterior resection
 18 April 2018 
Hep C treatment for sustained virologic response
 18 April 2018 
Endoscopic necrosectomy reduces risk of death 
 17 April 2018 
Colorectal cancer screening and ethnic inequities
 17 April 2018 
Training programs should consider radiation education for advanced endoscopy fellows
 17 April 2018 
Aspirin and pancreatic cancer
 16 April 2018 
Surgery for colorectal polyps has increased 
 16 April 2018 
Advanced fibrosis can be ruled out in primary health care patients
 16 April 2018 
Antibiotic use and colorectal adenoma
 13 April 2018 
Colorectal cancer cell lines
 13 April 2018 
Infliximab and corticosteroid-free clinical remission in Crohn's
 13 April 2018 
Teduglutide for children with short bowel syndrome
 12 April 2018 
Prescriptions for opiate drugs amongst primary care patients with IBD
 12 April 2018 
Lower GI bleeding related to comorbidity
 12 April 2018 
non–Clostridium difficile bacterial infections in IBD
 11 April 2018 
Physician perception of IBD trial results
 11 April 2018 
Bile acid deficiency in IBS 
 11 April 2018 
Stem cell therapy for fistulas in Crohn's
 10 April 2018 
Overweight in childhood and type 2 diabetes
 10 April 2018 
immunoglobulin G associates with clinical features of IBD
 10 April 2018 
T-cells repertoires in celiac disease
 09 April 2018 
Biomarker tests for colorectal cancer screening
 09 April 2018 
Fecal transplantation in C. difficile infection and treatment outcome 
 09 April 2018 
No weigh-loss drug improved all cardiometabolic risk factors
 06 April 2018 
Colonoscopy and colorectal cancer mortality
 06 April 2018 
Eosinophilic esophagitis and health-related quality of life
 06 April 2018 
Microbiome in athletes vs sedentary subjects
 05 April 2018 
Laparoscopic Nissen fundoplication for GERD treatment
 05 April 2018 
Random biopsies for neoplasia in IBD
 05 April 2018 
Scoring system identifies cancer risk in Barrett's
 04 April 2018 
Alpha‐1 antitrypsin deficiency and liver disease
 04 April 2018 
PPI and risk of stroke
 04 April 2018 
Adjuvant chemotherapy for advanced colon cancer
 29 March 2018 
Prevention of metachronous gastric cancer
 29 March 2018 
Acute lower GI bleeding
 28 March 2018 
Decision aid used by IBD patients
 28 March 2018 
Transition for young adults with IBD
 28 March 2018 
Amitriptyline in functional dyspepsia
 27 March 2018 
Emergency department utilization for IBD 
 27 March 2018 
Management of hemorrhoids in the USA
 27 March 2018 
Adult ulcerative colitis
 26 March 2018 
Biological therapy response in IBD 
 26 March 2018 
Obesity and diverticulosis
 26 March 2018 
Practice guidelines for chronic constipation
 23 March 2018 
Health-related quality of life in eosinophilic esophagitis
 23 March 2018 
Genetics and chronic liver disease
 23 March 2018 
Global prevalence of H.pylori
 22 March 2018 
H. pyloris and gastric cancer
 22 March 2018 
Pancreatitis after IBS treatment 
 22 March 2018 
Mechanisms of action in patients with IBS
 21 March 2018 
Panel markers for early detection of colon cancer

 21 March 2018 
Blood test differentiates celiac disease
 21 March 2018 
Patient characteristics and colonoscopy preparation
 20 March 2018 
Bloody vs coffee-grounds hematemesis

Blackwell Publishing


GastroHep.com is a Blackwell Publishing registered trademark
© 2018 Wiley-Blackwell and GastroHep.com and contributors
Privacy Statement
Disclaimer
About Us