Endoscopy is commonly performed to evaluate symptoms of dyspepsia.
Dr Lieberman and Colleagues from Oregon, USA undertook a study to characterize patients who receive endoscopy for dyspepsia.
The researchers measured predictors of primary endoscopic outcomes utilizing a large national endoscopic database.
The Clinical Outcomes Research Initiative (CORI) receives endoscopy reports from a network of 74 sites in the United States.
61% of reports that the group used had come from private practice settings.
The research group identified patients with reflux dyspepsia and nonreflux dyspepsia from January 2000 to June 2002.
The researchers excluded any patients with dysphagia and known Barrett’s esophagus.
Primary endoscopic outcomes included esophageal inflammation and stricture, gastric ulcer, duodenal ulcer, suspected Barrett’s esophagus (>=2cm), and suspected esophageal and gastric malignancy.
|Esophageal or gastric malignancy in patients with dyspepsia is associated with increasing age, male sex, Asian race and Native American race|
The research team noted the presence or absence of any alarm symptoms (vomiting, weight loss, and evidence of GI blood loss).
In total, the researchers collected information from 117,497 endoscopic reports, representing 99,558 unique patients.
The team found that dyspepsia, with and without reflux symptoms, accounted for 43% of upper endoscopies.
In addition, among dyspeptic patients, 36.5% were younger than 50 years of age without alarm symptoms.
The researchers found that esophageal or gastric malignancy in patients with dyspepsia was associated with increasing age, male sex, Asian race, Native American race, and symptoms of weight loss and vomiting.
The research group also found that suspected Barrett’s esophagus (>=2cm) was associated with reflux symptoms, male sex, age, and white race.
Ulcers were associated with evidence of bleeding, vomiting, male sex, black race, and Hispanic ethnicity.
Dr Lieberman concluded, "These practice-based data reveal important practice behaviors and outcomes."