The role of aspirin in increasing the risk of clinically significant post-polypectomy bleeding is unclear.
In this study, physicians from the United States determined whether aspirin use prior to colonoscopy increases the risk of clinically significant post-polypectomy bleeding.
The team performed a case-control study of patients with clinically significant post-polypectomy bleeding. The control group was made up of matched patients who had undergone polypectomy without any complications.
The team collected data on age, gender, recent use of aspirin or NSAIDs, polyp characteristics, and polypectomy technique.
During the study period, 20,636 patients underwent colonoscopy with polypectomy; 101 patients presented with clinically significant post-polypectomy bleeding.
The team excluded 20 patients from analysis because of prior anticoagulant use.
They matched the remaining 81 patients with 81 patients who had undergone colonoscopy without complications.
The physicians found that the 2 two groups were comparable in terms of polyp size.
The team determined that aspirin use prior to polypectomy was 40% in the bleeding group and 33% in the control group.
Dr Mahmoud Yousfi and colleagues concluded, "Postpolypectomy bleeding is an uncommon but important complication of endoscopic polypectomy".
"There was no statistically relevant difference in prior aspirin use before polypectomy in the bleeding group and the matched controls."