Laryngopharyngeal reflux disease arises from the effects of refluxed gastric contents on the proximal aerodigestive tract.
Laryngopharyngeal reflux symptoms are hoarseness, globus, cough, and pharyngitis; severe disease is associated with subglottic stenosis and laryngeal cancer.
In this study, physicians from the United States assessed 41 patients who underwent fundoplication for laryngopharyngeal reflux.
The team evaluated the patients using the Reflux Symptom Index, a laryngoscopic grading scale (Reflux Finding Score), and a reflux-based specific quality-of-life scale.
Average early follow-up was at 4 months and late follow-up was at 14 months.
|Structural laryngeal changes were associated with poor outcome.|
|Journal of the American College of Surgeons|
The team found that the Reflux Symptom Index improved by 5.4 at early follow-up and 6.5 at late.
In addition, the Reflux Finding Score improved by 3.8 at early follow-up and 4.4 at late follow-up.
The Quality of Life Index improved 0.6 early and 2.3 late.
The team found that factors associated with poor outcomes were structural laryngeal changes in 5 patients and no response to proton pump inhibitors in 6 patients.
Dr Carl Westcott's team concluded, "Fundoplication augments treatment of laryngopharyngeal reflux".
"Improvement of symptoms continues past the first 4 months".
"Laryngoscopy is critical in patient selection because selected findings are associated with outcomes, diagnosis, and management".