Peptic ulcer disease may be the cause of upper-GI bleeding in 50% of cases.
In this study, researchers from the United States evaluated the frequency of peptic ulcer in patients with upper-GI bleeding and the proportion of bleeding peptic ulcers with a non-bleeding visible vessel.
The research team included 126 patients with upper-GI bleeding who were seen between 1999 and 2001 in the study.
| 32% of patients had peptic ulcers.
They also used the Clinical Outcome Research Initiative (CORI) database to correlate their single institution data with nationwide data.
The team found that 32% of patients had peptic ulcers. A non-bleeding visible vessel was present in 10% of these peptic ulcers.
The team obtained data on 7822 patients with upper-GI bleeding using the CORI database.
For these patients, endoscopy established that 21% had peptic ulcers, and a non-bleeding visible vessel was present in 7% of the ulcers.
Dr Somprak Boonpongmanee‘s team concluded, “The frequency of peptic ulcer in patients with upper-GI bleeding and the proportion of bleeding ulcers with a non-bleeding visible vessel are less than previously reported“.