In this study, doctors from Rochester, Minnesota, compared prospectively with push enteroscopy in 20 patients with GI hemorrhage.
There were 20 patients enrolled in the study.
All patients had undergone non-diagnostic EGD, colonoscopy, and barium contrast radiography of the small bowel.
All patients underwent capsule endoscopy followed by push enteroscopy.
The physician performing the enteroscopy interpreted the capsule endoscopy in an unblinded manner. A second blinded reviewer interpreted the capsule endoscopy to establish interinterpreter reliability.
| Capsule endoscopy identified positive findings in 70% of patients.|
The doctors found that there was complete agreement between the blinded and the unblinded physicians in 18 of 20 cases. They found minor disparities the remaining 2 cases.
The team determined that in the small bowel, capsule endoscopy identified positive findings in 70% of patients, compared to 25% for push enteroscopy.
However, the findings were definitive in only 6 of the 20 patients by using capsule endoscopy, and in 2 of 20 patients with push enteroscopy.
Dr Douglas Adler's team concluded, "When strict standards of interpretation were used, capsule endoscopy resulted in more positive findings than push enteroscopy, but the number of definitive findings for both imaging methods was low".
"There was a high degree of reliability between a novice and an experienced endoscopist with respect to the interpretation of capsule endoscopy".