Patients with inflammatory bowel disease (IBD) are thought to be at increased risk of venous thromboembolism (TE). However, the extent of this risk is not known.
It is also not known whether the risk is specific for IBD or it is shared by other chronic inflammatory or chronic bowel diseases.
In this study, physicians from Vienna, Austria, compared the risk of TE in patients with IBD (n = 618), rheumatoid arthritis (n = 243), and celiac disease (n = 207) with matched control subjects (n = 707).
|At least 1 IBD specific factor was present when thromboembolism occurred in 60% of patients.|
All study subjects answered a questionnaire assessing the history of TE. Any reported cases had to be confirmed radiologically.
The team found that 6% of the IBD patients had suffered TE. They found that this was significantly higher than in the matched control group (2%)
Furthermore, 2% of patients with rheumatoid arthritis had suffered TE, compared with 3% of subjects in this group's matched control population.
In addition, 1% of patients with celiac disease had suffered TE, compared with 2% of the controls.
The team found that in 60% of TE cases in the IBD group, at least 1 IBD specific factor was present at the time TE occurred.
Dr Miehsler's team concluded, "IBD is a risk factor for TE".
"It seems that TE is a specific feature of IBD as neither rheumatoid arthritis…nor celiac disease…had an increased risk of TE".