Only a few studies have addressed coffee consumption and diabetes mellitus.
In this study, researchers determined the relationship between coffee consumption and the incidence of type 2 diabetes mellitus in Finland, where coffee consumption is the highest in the world.
The team performed a prospective study which combined surveys conducted in 1982, 1987, and 1992. The surveys included 6974 men and 7655 women aged 35 to 64 years. Participants had no history of stroke, coronary heart disease, or diabetes mellitus at baseline.
Coffee consumption and other study parameters were determined at baseline using standardized measurements.
The team calculated hazard ratios (HRs) for the incidence of type 2 diabetes mellitus at different levels of daily coffee consumption.
|In both sexes combined, the multivariate-adjusted inverse association was significant.|
|Journal of the American Medical Association|
During a mean follow-up of 12 years, there were 381 incident cases of type 2 diabetes mellitus.
After adjusting for confounding factors, the researchers determined the HRs of diabetes mellitus associated with the amount of coffee consumed daily. For women who consumed 0 to 2 cups, 3 to 4 cups, 5 to 6 cups, 7 to 9 cups, and 10 cups daily, HRs were 1.00, 0.71, 0.39, 0.39, and 0.21, respectively. For men the HRs were 1.00, 0.73, 0.70, 0.67, and 0.45, respectively.
The team determined that in both sexes combined, the multivariate-adjusted inverse association was significant.
Dr Jaakko Tuomilehto and colleagues concluded, "Coffee drinking has a graded inverse association with the risk of type 2 diabetes mellitus".
"However, the reasons for this risk reduction associated with coffee remain unclear".